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  • 中药标准品生产商,产品定制服务
  • 蒲公英赛酮

    Taraxerone

    蒲公英赛酮
    产品编号 CFN98821
    CAS编号 514-07-8
    分子式 = 分子量 C30H48O = 424.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The herbs of Taraxacum mongolicum Hand. Mazz.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    蒲公英赛酮 CFN98821 514-07-8 1mg QQ客服:1457312923
    蒲公英赛酮 CFN98821 514-07-8 5mg QQ客服:1457312923
    蒲公英赛酮 CFN98821 514-07-8 10mg QQ客服:1457312923
    蒲公英赛酮 CFN98821 514-07-8 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of East Anglia (United Kingdom)
  • Korea Food Research Institute(KFRI) (Korea)
  • University of Pretoria (South Africa)
  • Ain Shams University (Egypt)
  • University of Lodz (Poland)
  • Sri Ramachandra University (India)
  • Seoul National University (Korea)
  • University of Otago (New Zealand)
  • Cornell University (USA)
  • Universiti Malaysia Pahang (Malaysia)
  • Utrecht University (Netherlands)
  • Universidade do Porto (Portugal)
  • Guangzhou Institutes of Biomedicine and Health (China)
  • The Institute of Cancer Research (United Kingdom)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Biomol Ther (Seoul).2019, 10.4062
  • Nutrients.2023, 15(4):954.
  • Food Sci Biotechnol.2023, 32(9):1215-1223.
  • Nutrients.2023, 15(13):2960.
  • Plos One.2020, 10.1371
  • Inflammation2015, 38(1):445-55
  • Curr Eye Res.2018, 43(1):27-34
  • Heliyon2022, 8(2):e08866.
  • Biomed Pharmacother.2020, 128:110318.
  • Cardiovasc Toxicol.2021, 21(11):947-963.
  • Industrial Crops and Products2017, 95:286-295
  • Life Sci.2019, 216:259-270
  • Korean J. Medicinal Crop Sci.2018, 26(2):148-156
  • Toxicol Rep.2021, 8:1131-1142.
  • J Food Sci.2022, 87(11):4905-4916.
  • Molecules.2021, 26(2):E255.
  • Research Square2021, 10.21203.
  • J Sep Sci.2018, 41(7):1682-1690
  • J.of Traditional&Complementary Med.2022, 10.1016:j.jtcme.
  • Biosci Rep.2018, 38(4)
  • J Exp Bot.2016, 67(12):3777-88
  • Chin. Med.J.Res. Prac.2017, 31(4)
  • J Food Composition and Analysis2022, 104417.
  • ...
  • 生物活性
    Description: Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration with the concentration dependent manner.
    Targets: Antifection
    In vivo:
    Food Chem Toxicol. 2012 Jul;50(7):2508-14.
    Taraxerone enhances alcohol oxidation via increases of alcohol dehyderogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities and gene expressions.[Pubmed: 22554647]

    METHODS AND RESULTS:
    The present study, Taraxerone (d-friedoolean-14-en-3-one) was isolated from Sedum sarmentosum with purity 96.383%, and its enhancing effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities were determined: EC(50) values were 512.42 ± 3.12 and 500.16 ± 3.23 μM for ADH and ALDH, respectively. In order to obtain more information on Taraxerone related with the alcohol metabolism, 40% ethanol (5 mL/kg body weight) with 0.5-1mM of Taraxerone were administered to mice. The plasma alcohol and acetaldehyde concentrations of Taraxerone-treated groups were significantly lowered than those of the control group (p<0.01): approximately 20-67% and 7-57% lowered for plasma alcohol and acetaldehyde, respectively.
    CONCLUSIONS:
    Compare to the control group, the ADH and ALDH expressions in the liver tissues were abruptly increased in the Taraxerone-treated groups after ethanol exposure. In addition, Taraxerone prevented catalase, superoxide dismutase, and reduced glutathione concentrations from the decrease induced by ethanol administration with the concentration dependent manner.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.3546 mL 11.773 mL 23.546 mL 47.0921 mL 58.8651 mL
    5 mM 0.4709 mL 2.3546 mL 4.7092 mL 9.4184 mL 11.773 mL
    10 mM 0.2355 mL 1.1773 mL 2.3546 mL 4.7092 mL 5.8865 mL
    50 mM 0.0471 mL 0.2355 mL 0.4709 mL 0.9418 mL 1.1773 mL
    100 mM 0.0235 mL 0.1177 mL 0.2355 mL 0.4709 mL 0.5887 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    异蒲公英赛醇; Epitaraxerol CFN97789 20460-33-7 C30H50O = 426.73 5mg QQ客服:2159513211
    蒲公英赛醇; Taraxerol CFN99381 127-22-0 C30H50O = 426.7 5mg QQ客服:1457312923
    乙酰蒲公英萜醇; Taraxeryl acetate CFN98087 2189-80-2 C32H52O2 = 468.8 5mg QQ客服:215959384
    蒲公英赛酮; Taraxerone CFN98821 514-07-8 C30H48O = 424.7 5mg QQ客服:2056216494
    杨梅萜二醇,蒲公英赛-14-烯-3beta,28-二醇; Myricadiol CFN99839 17884-88-7 C30H50O2 = 442.7 5mg QQ客服:3257982914
    14,17-表二氧基-28-去甲-15-蒲公英烯-2,3-二醇; 14,17-Epidioxy-28-nor-15-taraxerene-2,3-diol CFN97129 66107-60-6 C29H46O4 = 458.7 5mg QQ客服:1413575084

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