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  • 大豆皂苷 Ba

    Soyasaponin Ba

    大豆皂苷 Ba
    产品编号 CFN90722
    CAS编号 114590-20-4
    分子式 = 分子量 C48H78O19 = 959.1
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The seeds of Glycine max
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    大豆皂苷 Ba CFN90722 114590-20-4 10mg QQ客服:1148253675
    大豆皂苷 Ba CFN90722 114590-20-4 20mg QQ客服:1148253675
    大豆皂苷 Ba CFN90722 114590-20-4 50mg QQ客服:1148253675
    大豆皂苷 Ba CFN90722 114590-20-4 100mg QQ客服:1148253675
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Perugia (Italy)
  • University of Toulouse (France)
  • Harvard University (USA)
  • Universitas islam negeri Jakarta (Indonesia)
  • Ain Shams University (Egypt)
  • Monash University Sunway Campus (Malaysia)
  • Korea Food Research Institute(KFRI) (Korea)
  • Instytut Nawozów Sztucznych w Pu?awach (Poland)
  • Aarhus University (Denmark)
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  • Universidad Miguel Hernández (Spain)
  • The University of Newcastle (Australia)
  • Wageningen University (Netherlands)
  • Universidad de Buenos Aires (Argentina)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • China Pharmacy2015, 26(27)
  • Acta Biochim Pol.2015, 62(2):253-8
  • University of Limpopo2016, 1-237
  • HortTechnology2016, 26(6):816-819
  • Food and Bioprocess Technology2017, 10(6):1074-1092
  • J Ethnopharmacol.2017, 198:205-213
  • Oncology Letters2018, 4690-4696
  • Arch Biochem Biophys.2018, 644:93-99
  • Nutrients.2019, 12(1)
  • Industrial Crops and Products2019, 140:111612
  • Nutr Metab (Lond).2019, 16:31
  • Evid Based Complement Alternat Med.2019, 2019:2135351
  • Molecules.2019, 24(1):E159
  • Molecules.2019, 24(10):E1930
  • Saudi Pharm J.2019, 27(1):145-153
  • Food Chem.2019, 275:746-753
  • Int J Immunopathol Pharmacol.2019, 33:2058738419857537
  • Journal of Apiculture2019, 34(2):131-136
  • J of Ana. Chem.2019, 74(11):1113-1121
  • Food Sci Nutr.2019, 8(1):246-256
  • Food Funct.2020, 10.1039
  • Antioxidants (Basel).2020, 9(2): E119
  • Cell Metab.2020, S1550-4131(20)30002-4
  • ...
  • 生物活性
    Description: Soyasaponins(Aa, Ab, Af, Ba, Bb, and Bb') together with their derivatives may represent viable candidates for effective vaccine adjuvants due to their higher and lower or non-haemolytic effects.Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without the inhibition of acetylcholinesterase.
    Targets: cAMP
    In vivo:
    J.Agr.Food Chem., 2014, 62(9):2062-8.
    Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without the inhibition of acetylcholinesterase.[Pubmed: 24450802 ]
    Soy (Glycine max, family Leguminosae), which contains isoflavones and saponins as main constituents, is known to exhibit memory-enhancing effects.
    METHODS AND RESULTS:
    Therefore, to investigate the role of soyasaponins in memory impairments, we isolated soyasaponin Ab (SA) and soyasaponin Bb (SB) from soybean and measured their protective effects against scopolamine-induced memory impairment in mice. SA and SB significantly prevented scopolamine-induced memory impairment in passive avoidance and Y-maze tasks. Compared to SA, SB rescued memory impairment more potently. Treatment with SB (10 mg/kg, p.o.) protected memory impairment in passive avoidance and Y-maze tasks to 97% (F = 68.10, P < 0.05) and 78% (F = 35.57, P < 0.05) of untreated normal control level, respectively. SA and SB (10 mg/kg) also rescued scopolamine-induced memory impairment in Morris water maze task (F = 14.51, P < 0.05). In addition, soyasaponins preserved brain-derived neurotrophic factor (BNDF) expression (F = 33.69, P < 0.05) and cAMP response element-binding (CREB) protein phosphorylation (F = 91.62, P < 0.05) in the hippocampus of scopolamine-treated mice. However, SA and SB did not inhibit acetylcholinesterase in vitro and ex vivo.
    CONCLUSIONS:
    On the basis of these findings, we suggest that soybean, particularly soyasaponins, may protect memory impairment by increasing BDNF expression and CREB phosphorylation.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.0426 mL 5.2132 mL 10.4264 mL 20.8529 mL 26.0661 mL
    5 mM 0.2085 mL 1.0426 mL 2.0853 mL 4.1706 mL 5.2132 mL
    10 mM 0.1043 mL 0.5213 mL 1.0426 mL 2.0853 mL 2.6066 mL
    50 mM 0.0209 mL 0.1043 mL 0.2085 mL 0.4171 mL 0.5213 mL
    100 mM 0.0104 mL 0.0521 mL 0.1043 mL 0.2085 mL 0.2607 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Pedunsaponin A; Pedunsaponin A CFN80329 250613-27-5 C42H66O15 = 811.0 5mg QQ客服:1148253675
    大豆皂苷Be甲酯; Soyasaponin Be methyl Ester CFN90777 N/A C49H78O18 = 955.2 5mg QQ客服:3257982914
    大豆皂苷Bd; Soyasaponin Bd CFN90775 N/A C48H76O19 = 957.1 5mg QQ客服:215959384
    大豆皂苷IV; Soyasaponin IV CFN93251 108906-97-4 C41H66O13 = 767.0 5mg QQ客服:215959384
    大豆皂苷II; Soyasaponin II CFN93159 55319-36-3 C47H76O17 = 913.1 5mg QQ客服:2159513211
    大豆皂苷Bb; Soyasaponin Bb CFN90456 51330-27-9 C48H78O18 = 943.12 20mg QQ客服:215959384
    大豆皂苷 Ba; Soyasaponin Ba CFN90722 114590-20-4 C48H78O19 = 959.1 20mg QQ客服:2932563308
    大豆皂苷Aa; Soyasaponin Aa CFN90455 117230-33-8 C64H100O31 = 1365.46 5mg QQ客服:2932563308
    大豆皂苷Ab; Soyasaponin Ab CFN90773 118194-13-1 C67H104O33 = 1437.6 5mg QQ客服:1148253675
    大豆皂苷Ac; Soyasaponin Ac CFN90774 133882-74-3 C67H104O32 = 1421.6 5mg QQ客服:1148253675

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