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  • 蛇根亭碱

    Serpentinine

    蛇根亭碱
    产品编号 CFN98499
    CAS编号 36519-42-3
    分子式 = 分子量 C42H44N4O5 = 684.8
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Alkaloids
    植物来源 The roots of Rauvolfia verticillata (Lour.) Baill.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    蛇根亭碱 CFN98499 36519-42-3 1mg QQ客服:1457312923
    蛇根亭碱 CFN98499 36519-42-3 5mg QQ客服:1457312923
    蛇根亭碱 CFN98499 36519-42-3 10mg QQ客服:1457312923
    蛇根亭碱 CFN98499 36519-42-3 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • Institute of Bioorganic Chemistry Polish Academy of Sciences (Poland)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Molecules.2017, 22(3)
  • Bulletin of Health Research2016, 44(4):279-286
  • Mol Cells.2018, 41(8):771-780
  • Antioxidants (Basel).2022, 11(10):1929.
  • Appl. Sci.2023, 13(17), 9653.
  • Sci Rep. 2018, 462(8)
  • Enzyme Microb Technol.2022, 161:110111.
  • Molecules.2023, 28(13):4971.
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  • Food Funct.2022, 13(13):6923-6933.
  • Korean Journal of Pharmacognosy.2020, 51(2):100-106
  • Processes2021, 9(1), 153;
  • Front Plant Sci.2018, 9:1424
  • FEMS Microbiol Lett.2017, 364(11)
  • Food Res Int.2021, 148:110607.
  • Applied Biological Chemistry 2021, 64(75)
  • Appl. Sci.2022, 12(17), 8646.
  • Front Pharmacol.2020, 11:683.
  • Evid Based Complement Alternat Med.2021, 2021:8707280.
  • J Appl Biol Chem.2022, 65(4):pp.463-469.
  • Korean J of Medicinal Crop Science2018, 220-226
  • J Cell Physiol.2020, 10.1002
  • J Med Food.2016, 19(12):1155-1165
  • ...
  • 生物活性
    Description: Serpentinine may have antihypertensive effect.
    In vitro:
    Current Hypertension Reviews,2010, 6(3):190-8.
    Resurgence of Herbal Antihypertensives in Management of Hypertension.[Reference: WebLink]
    Hypertension is one of the major cardiovascular problems and causes a number of vascular disorders. Until the 1940s majority of the diseases were treated by traditional drugs obtained from plants/herbs only. Even the first potent herbal antihypertensive was obtained from root of Rauwolfia serpentina, a famous Ayurvedic plant but soon the modern antihypertensives took the center-stage because of their precise, defined and fast action. However, due to their growing adverse effects, interest in the use of these drugs also gradually started waning. This has lead to the resurgence of marked awareness about traditional medicines and a considerable renewed global interest in the plant based drugs. Much emphasis is now being given to validate the extract/fraction as well as single molecules obtained from plant resources based on their traditional claims.
    METHODS AND RESULTS:
    In this review, we have laid emphasis on the mechanistic aspect of antihypertensive effect of some medicinal plants and their therapeutic use. We have further tried to shed light on the attempts being made for the validation and documentation of traditional plants and herbs for their future development as potential therapy in hypertension. What's already known? • The herbal medications had been used since long to treat various cardiovascular disorders including high blood pressure before the arrival of modern therapy. • Global interest has now been renewed in herbal medicines but need authentication and validation in support of their therapeutic value. What this article may add? • This review emphasizes the mechanistic aspect of herbal medicines, their therapeutic values in clinical situation as well as present measures and recent approaches to validate and document their antihypertensive efficacies.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.4603 mL 7.3014 mL 14.6028 mL 29.2056 mL 36.507 mL
    5 mM 0.2921 mL 1.4603 mL 2.9206 mL 5.8411 mL 7.3014 mL
    10 mM 0.146 mL 0.7301 mL 1.4603 mL 2.9206 mL 3.6507 mL
    50 mM 0.0292 mL 0.146 mL 0.2921 mL 0.5841 mL 0.7301 mL
    100 mM 0.0146 mL 0.073 mL 0.146 mL 0.2921 mL 0.3651 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    (4R)-阿马碱N-氧化物; 4,R-ajmalicine N-oxide CFN98652 41590-29-8 C21H24N2O4 = 368.4 5mg QQ客服:2159513211
    阿立新碱; Aricine CFN98760 482-91-7 C22H26N2O4 = 382.5 5mg QQ客服:2056216494
    萝巴新; 阿吗碱; Ajmalicine CFN98761 483-04-5 C21H24N2O3 = 352.4 5mg QQ客服:1413575084
    蛇纹石素; Serpentine CFN99867 18786-24-8 C21H21N2O3 = 349.4 5mg QQ客服:3257982914
    Rauvotetraphylline E; Rauvotetraphylline E CFN96746 1422506-53-3 C20H19N2O3 = 335.4 5mg QQ客服:215959384
    鸭脚木碱; Alstonine CFN97709 642-18-2 C21H21N2O3 = 349.4 5mg QQ客服:2159513211
    阿枯米精; Akuammigine CFN97710 642-17-1 C21H24N2O3 = 352.43 5mg QQ客服:3257982914
    Serpentinic acid; Serpentinic acid CFN97721 605-14-1 C20H19N2O3 = 335.38 5mg QQ客服:3257982914
    19-表阿马碱; Mayumbine CFN98283 25532-45-0 C21H24N2O3 = 352.4 5mg QQ客服:3257982914
    蛇根亭碱; Serpentinine CFN98499 36519-42-3 C42H44N4O5 = 684.8 5mg QQ客服:3257982914

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