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  • 半枝莲碱B

    Scutebarbatine B

    半枝莲碱B
    产品编号 CFN97471
    CAS编号 905929-95-5
    分子式 = 分子量 C33H35NO7 = 557.6
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Diterpenoids
    植物来源 The herbs of Scutellaria barbata D. Don.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    半枝莲碱B CFN97471 905929-95-5 1mg QQ客服:1457312923
    半枝莲碱B CFN97471 905929-95-5 5mg QQ客服:1457312923
    半枝莲碱B CFN97471 905929-95-5 10mg QQ客服:1457312923
    半枝莲碱B CFN97471 905929-95-5 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Chiang Mai University (Thailand)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Journal of Ginseng Research2019, 10.1016
  • Proc Natl Acad Sci USA.2016, 113(30):E4407-1
  • Evid Based Complement Alternat Med.2019, 2019:2135351
  • Evid Based Complement Alternat Med.2015, 2015:165457
  • Molecules.2018, 23(2)
  • Phytother Res.2015, 29(7):1088-96
  • Eur J Pharmacol.2020, 889:173589.
  • Food Structure2023, 36:100324.
  • PLoS One.2017, 12(3):e0173585
  • Appl. Sci.2020, 10,1304
  • Biomed Pharmacother.2022, 156:113929.
  • J Ethnopharmacol.2019, 236:31-41
  • Primary and Industrial.2018, 52(11)
  • Ulm University Medical Center2020, doi: 10.18725.
  • Neurotox Res.2020, 38(1):163-174.
  • Microorganisms.2021, 9(12):2514.
  • Current Pharmaceutical Analysis2017, 13(5)
  • Phytomedicine.2018, 47:48-57
  • Neurochem Res.2021, s11064-021-03449-0
  • Phytochemistry.2021, 181:112539.
  • Biomedicines.2021, 9(8):954.
  • J Sep Sci.2021, 44(22):4064-4081.
  • Phytomedicine.2018, 41:62-66
  • ...
  • 生物活性
    Description: Scutebarbatine B shows weak cytotoxicity with IC50 values ranging from 35.11 to 42.73 uM against K562 cell lines and HL60 cell lines.
    In vitro:
    J Asian Nat Prod Res. 2013 Sep;15(9):941-9.
    Bioassay-guided isolation of neo-clerodane diterpenoids from Scutellaria barbata.[Pubmed: 23909895]

    METHODS AND RESULTS:
    Bioassay-guided isolation of the aerial part of Scutellaria barbata yielded three new neo-clerodane diterpenoids scutebatas P-R (1-3), together with two known ones: scutebata E (4) and scutebarbatine B (5). The chemical structures of the isolated compounds were elucidated by spectroscopic methods (NMR and MS) and by comparison with the spectroscopic data reported in the literature.
    CONCLUSIONS:
    All compounds except 3 showed weak cytotoxicity with IC50 values ranging from 35.11 to 42.73 μM against K562 cell lines, and compounds 1, 2, and 5 also displayed weak activities against HL60 cell lines.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.7934 mL 8.967 mL 17.934 mL 35.868 mL 44.835 mL
    5 mM 0.3587 mL 1.7934 mL 3.5868 mL 7.1736 mL 8.967 mL
    10 mM 0.1793 mL 0.8967 mL 1.7934 mL 3.5868 mL 4.4835 mL
    50 mM 0.0359 mL 0.1793 mL 0.3587 mL 0.7174 mL 0.8967 mL
    100 mM 0.0179 mL 0.0897 mL 0.1793 mL 0.3587 mL 0.4484 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Scutebata B; Scutebata B CFN99323 1207181-58-5 C35H39NO10 = 633.7 5mg QQ客服:215959384
    Scutebata A; Scutebata A CFN99322 1207181-57-4 C36H40O10 = 632.7 5mg QQ客服:1457312923
    半枝莲碱 X; Scutebarbatine X CFN96691 1312716-26-9 C34H38N2O10 = 634.68 5mg QQ客服:1457312923
    16-Hydroxy-2-oxocleroda-3,13-dien-15,16-olide; 16-Hydroxy-2-oxocleroda-3,13-dien-15,16-olide CFN97965 165459-53-0 C20H28O4 = 332.4 5mg QQ客服:215959384
    (4->2)-Abeo-16-hydroxycleroda-2,13-dien-15,16-olide-3-al; (4->2)-Abeo-16-hydroxycleroda-2,13-dien-15,16-olide-3-al CFN89211 935293-70-2 C20H28O4 = 332.44 5mg QQ客服:1457312923
    6alpha,16,18-三羟基克罗-3,13-二烯-15,16-内酯; 6alpha,16,18-Trihydroxycleroda-3,13-dien-15,16-olide CFN97990 1017233-48-5 C20H30O5 = 350.5 5mg QQ客服:1457312923
    Dodovislactone B; Dodovislactone B CFN89104 1616683-55-6 C21H30O5 = 362.46 5mg QQ客服:1457312923
    半枝莲碱 Z ; Scutebarbatine Z CFN96683 1312716-28-1 C26H33NO5 = 439.55 5mg QQ客服:3257982914
    半枝莲碱 Y; Scutebarbatine Y CFN96686 1312716-27-0 C33H35NO7 = 557.64 5mg QQ客服:1457312923
    6-O-烟酰半枝莲素C; 6-O-Nicotinoylbarbatin C CFN99028 1015776-92-7 C26H31NO6 = 453.5 5mg QQ客服:2056216494

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