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  • 桧脂素, 洒维宁

    Savinin

    桧脂素, 洒维宁
    产品编号 CFN98786
    CAS编号 493-95-8
    分子式 = 分子量 C20H16O6 = 352.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Lignans
    植物来源 The heartwoods of Pterocarpus santalinus
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    桧脂素, 洒维宁 CFN98786 493-95-8 1mg QQ客服:2056216494
    桧脂素, 洒维宁 CFN98786 493-95-8 5mg QQ客服:2056216494
    桧脂素, 洒维宁 CFN98786 493-95-8 10mg QQ客服:2056216494
    桧脂素, 洒维宁 CFN98786 493-95-8 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Periyar University (India)
  • Molecular Biology Institute of Barcelona (IBMB)-CSIC (Spain)
  • Universidade Federal de Santa Catarina (Brazil)
  • Leibniz Institute of Plant Biochemistry (Germany)
  • Warszawski Uniwersytet Medyczny (Poland)
  • University of Limpopo (South Africa)
  • University of Toronto (Canada)
  • Institute of Tropical Disease Universitas Airlangga (Indonesia)
  • S.N.D.T. Women's University (India)
  • Nicolaus Copernicus Uniwersity (Poland)
  • Korea Food Research Institute(KFRI) (Korea)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • University of Auckland (New Zealand)
  • Kazusa DNA Research Institute (Japan)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Appl Biol Chem2021, 64(3):245-251.
  • Ann Transl Med.2019, 7(23):731
  • Sci Rep.2023, 13(1):21690.
  • Viruses.2021, 13(11):2118.
  • Molecules.2021, 26(2):313.
  • Biomed Pharmacother.2020, 131:110673.
  • ACS Synth Biol.2022, 11(10):3296-3304.
  • Exp Parasitol.2015, 153:160-4
  • Molecules.2018, 23(7):E1659
  • Toxicol Appl Pharmacol.2022, 434:115815.
  • Int J Mol Med.2015, 35(5):1237-45
  • Food Chem.2019, 274:345-350
  • Fitoterapia.2015, 100:179-86
  • Iranian J. Pharm. Res.2021, 20(4):59-70
  • Int J Mol Sci.2018, 19(9):E2528
  • Microchemical Journal2024: 196:109676.
  • Molecular & Cellular Toxicology2017, 13(3):271-278
  • bioRxiv - Molecular Biology2023, 535548.
  • Asian J Beauty Cosmetol2021, 19(1): 57-64.
  • Cell Signal.2022, 99:110433.
  • BMC Complement Altern Med.2018, 18(1):303
  • Appl. Sci. 2021, 11(22), 10552
  • Foods.2021, 10(11):2754.
  • ...
  • 生物活性
    Description: Savinin has antiinflammatory effect, can significantly inhibit tumor necrosis factor (TNF)-a production in lipopolysaccharide (LPS)-stimulated RAW264.7 cells, and T cell proliferation elicited by concanavalin (Con A), without displaying cytotoxicity. Savinin also exhibits potent spermicidal activity and significant insecticidal activity.
    Targets: TNF-α
    In vitro:
    Phytochemistry. 2001 Apr;56(8):857-61.
    Antimicrobial alkaloids from Zanthoxylum tetraspermum and caudatum.[Pubmed: 11324918 ]

    METHODS AND RESULTS:
    Two benzophenanthrene alkaloids, 8-acetonyldihydronitidine and 8-acetonyldihydroavicine were isolated from Zanthoxylum tetraspermum stem bark along with liriodenine, sesamin, lichexanthone and (+)-piperitol-gamma,gamma-dimethylallylether. The species endemic to Sri Lanka, Z. caudatum, contained sesamin, Savinin, liriodenine, decarine and 8-O-desmethyl-N-nornitidine.
    CONCLUSIONS:
    8-Acetonyldihydronitidine and 8-acetonyldihydroavicine showed significant antibacterial activity while the former along with liriodenine was strongly antifungal. Savinin exhibited potent spermicidal activity. Both Savinin and sesamin exhibited significant insecticidal activity.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.8385 mL 14.1924 mL 28.3849 mL 56.7698 mL 70.9622 mL
    5 mM 0.5677 mL 2.8385 mL 5.677 mL 11.354 mL 14.1924 mL
    10 mM 0.2838 mL 1.4192 mL 2.8385 mL 5.677 mL 7.0962 mL
    50 mM 0.0568 mL 0.2838 mL 0.5677 mL 1.1354 mL 1.4192 mL
    100 mM 0.0284 mL 0.1419 mL 0.2838 mL 0.5677 mL 0.7096 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Traxillaside; Traxillaside CFN96608 149415-62-3 C28H36O12 = 564.59 5mg QQ客服:1457312923
    Trachelosiaside; Trachelosiaside CFN89466 106647-12-5 C26H32O11 = 520.52 5mg QQ客服:1457312923
    Styraxlignolide F; Styraxlignolide F CFN92491 823214-06-8 C27H34O11 = 534.6 5mg QQ客服:215959384
    甲基牛蒡酚, 甲基牛蒡子素; 2,3-Bis(3,4-dimethoxybenzyl)butyrolactone CFN98281 25488-59-9 C22H26O6 = 386.4 5mg QQ客服:1413575084
    Tupichilignan A; Tupichilignan A CFN97182 69586-96-5 C22H26O7 = 402.4 5mg QQ客服:1413575084
    5-乙酰氧基罗汉松脂酚二甲醚; 5-Acetoxymatairesinol dimethyl ether CFN97230 74892-45-8 C24H28O8 = 444.5 5mg QQ客服:1457312923
    Pluviatolide; Pluviatolide CFN92059 28115-68-6 C20H20O6 = 356.4 5mg QQ客服:3257982914
    Kaerophyllin; Kaerophyllin CFN97234 75590-33-9 C21H20O6 = 368.4 5mg QQ客服:1413575084
    Meridinol; Meridinol CFN99313 120051-54-9 C20H18O7 = 370.4 5mg QQ客服:1413575084
    桧脂素, 洒维宁; Savinin CFN98786 493-95-8 C20H16O6 = 352.3 5mg QQ客服:2159513211

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