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  • 土大黄苷 6''-O-没食子酸酯

    Rhaponticin 6''-O-gallate

    土大黄苷 6''-O-没食子酸酯
    产品编号 CFN91099
    CAS编号 94356-23-7
    分子式 = 分子量 C28H28O13 = 572.51
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Miscellaneous
    植物来源 The roots of Rumex obtusifolius L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    土大黄苷 6''-O-没食子酸酯 CFN91099 94356-23-7 1mg QQ客服:1413575084
    土大黄苷 6''-O-没食子酸酯 CFN91099 94356-23-7 5mg QQ客服:1413575084
    土大黄苷 6''-O-没食子酸酯 CFN91099 94356-23-7 10mg QQ客服:1413575084
    土大黄苷 6''-O-没食子酸酯 CFN91099 94356-23-7 20mg QQ客服:1413575084
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
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    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Ind Crops Prod.2014, 62:173-178
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  • ...
  • 生物活性
    Description: Rhaponticin 6''-O-gallate showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM).
    Targets: NO
    In vitro:
    Bioorg Med Chem Lett. 2000 Feb 21;10(4):323-7.
    Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages.[Pubmed: 10714491 ]

    METHODS AND RESULTS:
    Two new anthraquinone glucosides [chrysophanol 8-O-beta-D-(6'-galloyl)-glucopyranoside, aloe-emodin 1-O-beta-D-glucopyranoside] together with various known stilbenes and their glucosides, anthraquinone glucosides, and a naphthalene glucoside were isolated from the rhizome of Rheum undulatum L. Three stilbenes (rhapontigenin, piceatannol, resveratrol), a naphthalene glucoside (torachrysone 8-O-beta-D-glucopyranoside), and two stilbene glucoside gallates (rhaponticin 2''-O-gallate, Rhaponticin 6''-O-gallate) showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM).
    CONCLUSIONS:
    The oxygen functions (-OH,-OCH3) at the benzene ring were found to be essential to show the activity. Whereas, the glucoside moiety reduced the activity, while the alpha,beta-double bond did not affect the activity. Furthermore, the active stilbenes (rhapontigenin, piceatannol, resveratrol) inhibited iNOS induction.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.7467 mL 8.7335 mL 17.4669 mL 34.9339 mL 43.6674 mL
    5 mM 0.3493 mL 1.7467 mL 3.4934 mL 6.9868 mL 8.7335 mL
    10 mM 0.1747 mL 0.8733 mL 1.7467 mL 3.4934 mL 4.3667 mL
    50 mM 0.0349 mL 0.1747 mL 0.3493 mL 0.6987 mL 0.8733 mL
    100 mM 0.0175 mL 0.0873 mL 0.1747 mL 0.3493 mL 0.4367 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    二氢白藜芦醇3-O-葡萄糖甙; Dihydroresveratrol 3-O-glucoside CFN99021 100432-87-9 C20H24O8 = 392.4 5mg QQ客服:1413575084
    去氧土大黄苷元; Desoxyrhapontigenin CFN90854 33626-08-3 C15H14O3 = 242.3 10mg QQ客服:2159513211
    去氧土大黄苷; Desoxyrhaponticin CFN90911 30197-14-9 C21H24O8 = 404.4 20mg QQ客服:215959384
    土大黄苷 6''-O-没食子酸酯; Rhaponticin 6''-O-gallate CFN91099 94356-23-7 C28H28O13 = 572.51 5mg QQ客服:215959384
    土大黄苷 2''-O-没食子酸酯; Rhaponticin 2''-O-gallate CFN91100 94356-24-8 C28H28O13 = 572.51 5mg QQ客服:215959384
    2,3,5,4-四羟基二苯乙烯葡萄糖苷; 2,3,5,4'-Tetrahydroxyl diphenylethylene-2-O-glucoside CFN99995 82373-94-2 C20H22O9 = 406.39 20mg QQ客服:215959384
    松茋; Pinostilbene CFN98662 42438-89-1 C15H14O3 = 242.3 5mg QQ客服:2932563308
    Pinostilbenoside; Pinostilbenoside CFN98995 58762-96-2 C21H24O8 = 404.4 5mg QQ客服:2159513211
    3-羟基-5-甲氧基二苯乙烯; 5-Methoxy-3-stilbenol CFN92587 5150-38-9 C15H14O2 = 226.3 5mg QQ客服:2932563308
    Thunalbene; Thunalbene CFN92783 220862-05-5 C15H14O3 = 242.3 5mg QQ客服:215959384

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