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  • 3,4-二羟基苯甲酸甲酯

    Protocatechuic acid methyl ester

    3,4-二羟基苯甲酸甲酯
    产品编号 CFN92634
    CAS编号 2150-43-8
    分子式 = 分子量 C8H8O4 = 168.2
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The stems of Bauhinia manca
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
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    3,4-二羟基苯甲酸甲酯 CFN92634 2150-43-8 10mg QQ客服:2159513211
    3,4-二羟基苯甲酸甲酯 CFN92634 2150-43-8 20mg QQ客服:2159513211
    3,4-二羟基苯甲酸甲酯 CFN92634 2150-43-8 50mg QQ客服:2159513211
    3,4-二羟基苯甲酸甲酯 CFN92634 2150-43-8 100mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Cell Mol Biol(Noisy-le-grand)2019, 65(7):77-83
  • Evid Based Complement Alternat Med.2021, 2021:6687513.
  • Phytother Res.2023, 37(10):4587-4606.
  • Current Pharmaceutical Analysis2017, 13(5)
  • LWT2020, 124:109163
  • iScience.2020, 23(2):100849.
  • Molecules.2018, 23(9):E2121
  • Evid Based Complement Alternat Med.2018, 2018:4259603
  • Foods.2021, 10(12):2929.
  • Biomed Pharmacother.2023, 163:114785.
  • J Biochem Mol Toxicol.2020, 34(7):e22489.
  • BMB Rep.2018, 51(5):249-254
  • Functional Ecology2020, doi: 10.1111.
  • VNU Journal of Science: Med.& Pharm. Sci.2022, 38(2):2588-1132.
  • J Pharm Biomed Anal.2019, 172:268-277
  • J Nat Med.2017, 71(2):380-388
  • J Agric Food Chem.2021, 69(14):4210-4222.
  • Biomed Pharmacother.2020, 125:109784.
  • J Agric Food Chem.2019, 67(27):7748-7754
  • LWT2020, 110397
  • J Nat Med.2017, 71(2):457-462
  • Appl Microbiol Biotechnol.2016, 100(9):3965-77
  • Phytomedicine.2018, 47:48-57
  • ...
  • 生物活性
    Description: Protocatechuic acid methyl ester has antiradical,and antimicrobial activities.
    Targets: Antifection
    In vitro:
    Food Chem. 2014 Aug 1;156:312-8.
    Degradation of cyanidin-3-rutinoside and formation of protocatechuic acid methyl ester in methanol solution by gamma irradiation.[Pubmed: 24629974]
    Anthocyanins are naturally occurring phenolic compounds having broad biological activities including anti-mutagenesis and anti-carcinogenesis.
    METHODS AND RESULTS:
    We studied the effects and the degradation mechanisms of the most common type of anthocyanins, cyanidin-3-rutinoside (cya-3-rut), by using gamma ray. Cya-3-rut in methanol (1mg/ml) was exposed to gamma-rays from 1 to 10kGy. We found that the reddish colour of cya-3-rut in methanol disappeared gradually in a dose-dependent manner and effectively disappeared (>97%) at 10kGy of gamma ray. Concomitantly, a new phenolic compound was generated and identified as a protocatechuic acid methyl ester by liquid chromatography, (1)H, and (13)C NMR.
    CONCLUSIONS:
    The formation of protocatechuic acid methyl ester increased with increasing irradiation and the amount of protocatechuic acid methyl ester formed by decomposition of cya-3-rut (20μg) at 10kGy of gamma ray was 1.95μg. In addition, the radical-scavenging activities were not affected by gamma irradiation.
    J Nat Prod. 2014 Feb 28;77(2):424-8.
    Sorbicatechols A and B, antiviral sorbicillinoids from the marine-derived fungus Penicillium chrysogenum PJX-17.[Pubmed: 24495078]

    METHODS AND RESULTS:
    Two novel sorbicillinoids combining a bicyclo[2.2.2]octane with a 2-methoxyphenol moiety, named sorbicatechols A (1) and B (2), were isolated from the culture of the marine sediment-derived fungus Penicillium chrysogenum PJX-17, together with the known Protocatechuic acid methyl ester and caffeic acid methyl ester (3). Their structures, including absolute configurations, were assigned by analysis of NMR, MS data, and TDDFT ECD calculations.
    CONCLUSIONS:
    Compounds 1 and 2 exhibited activities against influenza virus A (H1N1), with IC50 values of 85 and 113 μ M, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.9453 mL 29.7265 mL 59.453 mL 118.9061 mL 148.6326 mL
    5 mM 1.1891 mL 5.9453 mL 11.8906 mL 23.7812 mL 29.7265 mL
    10 mM 0.5945 mL 2.9727 mL 5.9453 mL 11.8906 mL 14.8633 mL
    50 mM 0.1189 mL 0.5945 mL 1.1891 mL 2.3781 mL 2.9727 mL
    100 mM 0.0595 mL 0.2973 mL 0.5945 mL 1.1891 mL 1.4863 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    3,4-二甲氧基苯甲酸; 3,4-Dimethoxybenzoic acid CFN97499 93-07-2 C9H10O4 = 182.2 20mg QQ客服:1413575084
    2,5-二羟基苯甲酸; Gentisic acid CFN92451 490-79-9 C7H6O4 = 154.1 20mg QQ客服:215959384
    Orsellinic acid; Orsellinic acid CFN96277 480-64-8 C8H8O4 = 168.2 5mg QQ客服:1457312923
    3-甲基-4-硝基苯甲酸; 3-Methyl-4-nitrobenzoic acid CFN90115 3113-71-1 C8H7NO4 = 181.15 5mg QQ客服:1457312923
    3,4-二羟基苯乙酮; 3',4'-Dihydroxyacetophenone CFN97903 1197-09-7 C8H8O3 = 152.2 20mg QQ客服:2056216494
    香草醇; Vanillyl alcohol CFN93211 498-00-0 C8H10O3 = 154.17 20mg QQ客服:215959384
    3,4-二羟基苯乙醇; 2-(3,4-Dihydroxyphenyl)ethanol CFN99076 10597-60-1 C8H10O3 = 154.2 20mg QQ客服:2056216494
    北升麻宁; Cimidahurinine CFN99465 142542-89-0 C14H20O8 = 316.3 5mg QQ客服:3257982914
    3,4-二羟基苯基二醇; 3,4-Dihydroxyphenylglycol CFN98355 28822-73-3 C8H10O4 = 170.2 5mg QQ客服:1413575084
    4-(2-羟基-1-甲氧基乙基)-1,2-苯二酚; 4-(2-Hydroxy-1-methoxyethyl)-1,2-benzenediol CFN98979 577976-26-2 C9H12O4 = 184.2 5mg QQ客服:1413575084

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