松茋

Pinostilbene

	产品编号	CFN98662
	CAS编号	42438-89-1
	分子式 = 分子量	C₁₅H₁₄O₃ = 242.3
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Phenols
	植物来源	The seeds of Vitis riparia.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

提供自定义包装

产品名称	产品编号	CAS编号	包装	QQ客服
松茋	CFN98662	42438-89-1	1mg	QQ客服：3257982914
松茋	CFN98662	42438-89-1	5mg	QQ客服：3257982914
松茋	CFN98662	42438-89-1	10mg	QQ客服：3257982914
松茋	CFN98662	42438-89-1	20mg	QQ客服：3257982914

存储与注意事项

1. 在您收到产品后请检查产品。如无问题，请将产品存入冰霜并且样品瓶保持密封，产品可以存放长达24个月（2-8摄氏度）。

2. 只要有可能，产品溶解后，您应该在同一天应用于您的实验。但是，如果您需要提前做预实验，或者需要全部溶解，我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。通常，这些可用于长达两周。使用前，打开样品瓶前，我们建议您将产品平衡至室温至少1小时。

3. 需要更多关于溶解度，使用和处理的建议？请发送电子邮件至：service@chemfaces.com

订购流程

1. 在线订购

请联系我们QQ客服

2. 电话订购

请拨打电话：
027-84237683 或 027-84237783

3. 邮件或传真订购

发送电子邮件到: manager@chemfaces.com 或
发送传真到：027-84254680

提供订购信息

为了方便客户的订购，请需要订购ChemFaces产品的客户，在下单的时候请提供下列信息，以供我们快速为您建立发货信息。

1. 产品编号（CAS No.或产品名称）

2. 发货地址

3. 联系方法 (联系人，电话）

4. 开票抬头 (如果需要发票的客户）

5. 发票地址（发货地址与发票地址不同）

发货时间

1. 付款方式为100%预付款客户，我们将在确认收到货款后当天或1-3个工作日发货。

2. 付款方式为月结的客户，我们承诺在收到订单后当天或1-3个工作日内发货。

3. 如果客户所需要的产品，需要重新生产，我们有权告知客户，交货时间需要延期。

ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Universidade da Beira Interior (Germany)

Tohoku University (Japan)

Universidad de Ciencias y Artes de Chiapas (Mexico)

Charles Sturt University (Denmark)

Leibniz Institute of Plant Biochemistry (Germany)

Weizmann Institute of Science (Israel)

Nicolaus Copernicus Uniwersity (Poland)

Universidade de Franca (Brazil)

National Chung Hsing University (Taiwan)

Amity University (India)

Kyoto University (Japan)

University of the Basque Country (Spain)

Universidade Federal de Pernambuco (UFPE) (Brazil)

The Institute of Cancer Research (United Kingdom)

More...

Description:

Pinostilbene has protective effects against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells, it can reduce release of lactate dehydrogenase and activity of caspase-3 triggered by 6-hydroxydopamine (6-OHDA) in a dose-dependent manner. Pinostilbene can significantly inhibit the growth of human colon cancer cells, i.e., HCT116 and HT29, 20 and 40 uM of pinostilbene causes cell cycle arrest at S phase and induces apoptosis in colon cancer cells.

Targets:

Caspase | JNK

In vitro:

J Nutr Biochem. 2010 Jun;21(6):482-9.

Protective effects of pinostilbene, a resveratrol methylated derivative, against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells.[Pubmed: 19443200]

Release of lactate dehydrogenase and activity of caspase-3 triggered by 6-OHDA were significantly reduced by resveratrol and one of the methylated derivatives, Pinostilbene (3,4'-dihydroxy-5-methoxystilbene), in a dose-dependent manner. In addition, Pinostilbene exerted a potent neuroprotective effect with a wider effective concentration range than resveratrol.
METHODS AND RESULTS:
By using high-performance liquid chromatography, we found that uptake of Pinostilbene into SH-SY5Y cells was significantly higher than that of resveratrol. Enhanced bioavailability may thus be a major factor contributing to the neuroprotective activity of Pinostilbene. Moreover, Western blot analysis demonstrated that Pinostilbene markedly attenuated the phosphorylation of JNK and c-Jun triggered by 6-OHDA. Besides, mammalian target of rapamycin kinase may be an intracellular target accounting for the neuroprotective effects of Pinostilbene.
CONCLUSIONS:
Our findings demonstrate the potential of methylated stilbenes in neuroprotection and provide important information for further research in this field.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
3,5-二甲氧基-3'-羟基联苄; 3,5-Dimethoxy-3'-hydroxybibenzyl	CFN89540	168281-05-8	C₁₆H₁₈O₃ = 258.31	5mg	QQ客服：2056216494
脱氧茴香偶姻; Desoxyanisoin	CFN90118	120-44-5	C₁₆H₁₆O₃ = 256.30	5mg	QQ客服：1413575084
Arundinin; Arundinin	CFN91179	148225-38-1	C₂₂H₂₂O₄ = 350.4	5mg	QQ客服：1457312923
2-(2,4-Dihydroxyphenyl)-5,6-methylenedioxybenzofuran (ABF); 2-(2,4-Dihydroxyphenyl)-5,6-methylenedioxybenzofuran (ABF)	CFN95511	67121-26-0	C₁₅H₁₀O₅ = 270.2	5mg	QQ客服：2056216494
白藜芦醇; Resveratrol	CFN98791	501-36-0	C₁₄H₁₂O₃ = 228.2	20mg	QQ客服：2056216494
乙酰白藜芦醇; Triacetylresveratrol	CFN90895	42206-94-0	C₂₀H₁₈O₆ = 354.4	20mg	QQ客服：2159513211
虎杖甙; Polydatin	CFN99159	27208-80-6	C₂₀H₂₂O₈ = 390.40	20mg	QQ客服：2159513211
白藜芦醇-3-O-β-D-(2''-O-没食子酰)-葡萄糖苷; Pieceid-2''-O-gallate	CFN95226	64898-03-9	C₂₇H₂₆O₁₂ = 542.5	10mg	QQ客服：1413575084
二氢藜芦醇; Dihydroresveratrol	CFN98987	58436-28-5	C₁₄H₁₄O₃ = 230.3	20mg	QQ客服：2056216494
二氢白藜芦醇3-O-葡萄糖甙; Dihydroresveratrol 3-O-glucoside	CFN99021	100432-87-9	C₂₀H₂₄O₈ = 392.4	5mg	QQ客服：2056216494

信息支持

公司简介
订购流程
付款方式
退换货政策

ChemFaces提供的产品仅用于科学研究使用，不用于诊断或治疗程序。

联系方式

电机：027-84237783
传真：027-84254680
在线QQ: 1413575084
E-Mail：manager@chemfaces.com

湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房

ChemFaces为科学家，科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产。

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.1271 mL	20.6356 mL	41.2712 mL	82.5423 mL	103.1779 mL
5 mM	0.8254 mL	4.1271 mL	8.2542 mL	16.5085 mL	20.6356 mL
10 mM	0.4127 mL	2.0636 mL	4.1271 mL	8.2542 mL	10.3178 mL
50 mM	0.0825 mL	0.4127 mL	0.8254 mL	1.6508 mL	2.0636 mL
100 mM	0.0413 mL	0.2064 mL	0.4127 mL	0.8254 mL	1.0318 mL