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  • 茂藿苷A

    Maohuoside A

    茂藿苷A
    产品编号 CFN98523
    CAS编号 128988-55-6
    分子式 = 分子量 C27H32O12 = 548.5
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Flavonoids
    植物来源 The roots of Epimedium brevicornu Maxim
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    茂藿苷A CFN98523 128988-55-6 1mg QQ客服:3257982914
    茂藿苷A CFN98523 128988-55-6 5mg QQ客服:3257982914
    茂藿苷A CFN98523 128988-55-6 10mg QQ客服:3257982914
    茂藿苷A CFN98523 128988-55-6 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of South Australia (Australia)
  • Korea Food Research Institute(KFRI) (Korea)
  • University of Fribourg (Switzerland)
  • Georgia Institute of Technology (USA)
  • Cancer Research Initatives Foundation(CARIF) (Malaysia)
  • Sanford Burnham Prebys Medical Discovery Institute (USA)
  • FORTH-IMBB (Greece)
  • University of Wollongong (Australia)
  • Northeast Normal University Changchun (China)
  • The Ohio State University (USA)
  • University of East Anglia (United Kingdom)
  • Universidade Federal de Goias (UFG) (Brazil)
  • University of Vienna (Austria)
  • University of Eastern Finland (Finland)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Chemistry of Plant Materials.2019, 129-136
  • Evid Based Complement Alternat Med.2021, 8855980.
  • Industrial Food Engineering2015, 19(4):408-413
  • Int J Mol Sci.2018, 19(9):E2825
  • Cancers (Basel).2023, 15(1):37.
  • Korean J. Medicinal Crop Sci.2022, 30(2):124-133
  • South African Journal of Botany2021, 142:114-123.
  • iScience.2020, 23(2):100849.
  • Molecules2022, 27(9):2613.
  • Nat Prod Sci.2018, 24(2):109-114
  • Inflammation2015, 38(1):445-55
  • The Korea Society of Pha.2014, 300-314
  • Food Sci Biotechnol.2023, 32(9):1215-1223.
  • Evid Based Complement Alternat Med.2018, 2018:8565132
  • Aquaculture2017, 481:94-102
  • Molecules.2019, 24(6):E1177
  • Int J Pharmacol2020, 16:1-9
  • Chinese Medicine2019, 14(1)
  • Kasetsart University2022, ethesis.1144.
  • Appl. Sci. 2021, 11(10),4666.
  • Pharmaceutics.2020, 12(9):882.
  • Journal of Chromatography A2020, 460942
  • Molecules.2019, 24(7):E1290
  • ...
  • 生物活性
    Description: Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.
    Targets: MAPK
    In vivo:
    Phytother Res. 2013 Aug;27(8):1179-84.
    Maohuoside A acts in a BMP-dependent manner during osteogenesis.[Pubmed: 23007945]
    There has been a strong interest in searching for natural therapies for osteoporosis. Epimedium koreanum Nakai is an herb that is commonly used in East Asia to treat osteoporosis, and most studies of its activity have focused on its major ingredient, icariin.
    METHODS AND RESULTS:
    In this study, Maohuoside A (MHA), a single compound isolated from the E. koreanum, was found to promote osteogenesis in mouse bone marrow-derived mesenchymal stem cells. We hypothesise that, if Maohuoside A potently induces osteogenic differentiation in a bone morphogenetic protein-dependent manner, it may be used to broaden the sources for cell transplantation and thereby establish more efficient bone regeneration systems. Real-time polymerase chain reaction and western blot were used to detect the expression of SMAD4, a marker of bone formation. Microcomputed tomography and histomorphometric techniques showed that oral treatment with Maohuoside A was followed by an increase in the bone mineral density of the lumbar vertebrae in mice. This result also indicates that Maohuoside A may directly activate osteopontin gene transcription.
    CONCLUSIONS:
    In conclusion, Maohuoside A seems to enhance the osteogenesis of bone marrow-derived mesenchymal stem cells at least partly via bone morphogenetic protein signalling.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8232 mL 9.1158 mL 18.2315 mL 36.4631 mL 45.5789 mL
    5 mM 0.3646 mL 1.8232 mL 3.6463 mL 7.2926 mL 9.1158 mL
    10 mM 0.1823 mL 0.9116 mL 1.8232 mL 3.6463 mL 4.5579 mL
    50 mM 0.0365 mL 0.1823 mL 0.3646 mL 0.7293 mL 0.9116 mL
    100 mM 0.0182 mL 0.0912 mL 0.1823 mL 0.3646 mL 0.4558 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    箭藿苷C; Sagittatoside C CFN92077 118525-37-4 C35H42O16 = 718.7 5mg QQ客服:2159513211
    异箭藿苷A; Iso-sagittatoside A CFN91155 503456-08-4 C33H40O15 = 676.7 5mg QQ客服:2159513211
    朝鲜淫羊藿苷A;朝藿苷甲; Korepimedoside A CFN92905 106441-31-0 C37H44O17 = 760.74 5mg QQ客服:2159513211
    宝藿苷VII; Baohuoside VII CFN90765 119730-89-1 C33H40O15 = 676.7 10mg QQ客服:1457312923
    淫羊藿苷; Icariin CFN99554 489-32-7 C33H40O15 = 676.65 20mg QQ客服:1413575084
    朝藿定B; Epimedin B CFN99940 110623-73-9 C38H48O19 = 808.78 20mg QQ客服:215959384
    朝藿定B1; Epimedin B1 CFN95017 133137-58-3 C38H48O19 = 808.8 5mg QQ客服:1457312923
    茂藿苷B; Maohuoside B CFN91887 849834-04-4 C39H50O20 = 838.80 5mg QQ客服:215959384
    朝藿定C; Epimedin C CFN99941 110642-44-9 C39H50O19 = 822.80 20mg QQ客服:3257982914
    朝藿定A1; Epimedin A1 CFN99145 140147-77-9 C39H50O20 = 838.8 20mg QQ客服:2159513211

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