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  • 杨梅酮3-O-半乳糖苷

    Myricetin 3-O-galactoside

    杨梅酮3-O-半乳糖苷
    产品编号 CFN97817
    CAS编号 15648-86-9
    分子式 = 分子量 C21H20O13 = 480.38
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Flavonoids
    植物来源 The root barks of Myrica cerifera L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    杨梅酮3-O-半乳糖苷 CFN97817 15648-86-9 1mg QQ客服:2159513211
    杨梅酮3-O-半乳糖苷 CFN97817 15648-86-9 5mg QQ客服:2159513211
    杨梅酮3-O-半乳糖苷 CFN97817 15648-86-9 10mg QQ客服:2159513211
    杨梅酮3-O-半乳糖苷 CFN97817 15648-86-9 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Maryland (USA)
  • University of Liège (Belgium)
  • Seoul National University (Korea)
  • National Research Council of Canada (Canada)
  • Chiang Mai University (Thailand)
  • Universidade de Franca (Brazil)
  • Shanghai University of TCM (China)
  • University of Bordeaux (France)
  • Uniwersytet Gdański (Poland)
  • Nicolaus Copernicus Uniwersity (Poland)
  • University of Melbourne (Australia)
  • VIT University (India)
  • Instituto Politécnico de Bragan?a (Portugal)
  • University Medical Center Mainz (Germany)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Pharmacogn J.2022, 14(2):350-357
  • Evid-Based Compl Alt2020, 7202519:13
  • Int J Mol Sci.2020, 21(19):7209.
  • Rev. Chim.2020, 71(3),558-564
  • Molecules.2023, 28(9):3685.
  • J Mol Recognit.2020, 33(2):e2819
  • Nutraceutical Research . 2021, 19(1),p90-105.
  • J Sci Food Agric.2017, 97(5):1656-1662
  • Front Pharmacol.2023, 14:1095083.
  • Phytomedicine.2022, 99:153997.
  • Am J Chin Med.2016, 44(6):1255-1271
  • Indian J Pharm Sci.2022, 84(4): 874-882.
  • Drug Des Devel Ther.2020, 14:5189-5204.
  • Comp. & Mathematical Methods in Med.2022, 5475559.
  • Asian J Beauty Cosmetol2022, 20(2):183-191
  • Life Sci.2022, 311(Pt A):121157.
  • Journal of Functional Foods2022, 91:105019.
  • Microchemical Journal2018, 137:168-173
  • Industrial Crops and Products2021, 163:113313.
  • Molecules.2022, 27(7):2116.
  • ACS Pharmacol. Transl. Sci.2022, 5,7,479-490
  • Appl. Sci. 2021, 11(8),3437.
  • Key Engineering Materials2022, 931(47-53).
  • ...
  • 生物活性
    Description: Myricetin 3-O-galactoside has cytotoxicity, antioxidant, anti-genotoxic, antinociceptive and anti-inflammatory effects, the effects are related to peripheral inhibition of nitric oxide synthesis, mainly inducible nitric oxide synthase (iNOS).
    Targets: PARP | NOS | NO
    In vitro:
    Toxicol In Vitro. 2008 Apr;22(3):567-81.
    In vitro antioxidant and antigenotoxic potentials of myricetin-3-o-galactoside and myricetin-3-o-rhamnoside from Myrtus communis: modulation of expression of genes involved in cell defence system using cDNA microarray.[Pubmed: 18222061]
    Antioxidant activity of Myricetin 3-O-galactoside and myricetin-3-o-rhamnoside, isolated from the leaves of Myrtus communis, was determined by the ability of each compound to inhibit xanthine oxidase activity, lipid peroxidation and to scavenge the free radical 1,1-diphenyl-2-picrylhydrazyl.
    METHODS AND RESULTS:
    Antimutagenic activity was assessed using the SOS chromotest and the Comet assay. The IC50 values of lipid peroxidation by Myricetin 3-O-galactoside and myricetin 3-o-rhamnoside are respectively 160 microg/ml and 220 microg/ml. At a concentration of 100 microg/ml, the two compounds showed the most potent inhibitory effect of xanthine oxidase activity by respectively, 57% and 59%. Myricetin 3-o-rhamnoside was a very potent radical scavenger with an IC50 value of 1.4 microg/ml. Moreover, these two compounds induced an inhibitory activity against nifuroxazide, aflatoxine B1 and H2O2 induced mutagenicity.
    CONCLUSIONS:
    The protective effect exhibited by these molecules was also determined by analysis of gene expression as response to an oxidative stress using a cDNA micro-array. Myricetin 3-O-galactoside and myricetin 3-o-rhamnoside modulated the expression patterns of cellular genes involved in oxidative stress, respectively (GPX1, TXN, AOE372, SEPW1, SHC1) and (TXNRD1, TXN, SOD1 AOE372, SEPW1), in DNA damaging repair, respectively (XPC, LIG4, RPA3, PCNA, DDIT3, POLD1, XRCC5, MPG) and (TDG, PCNA, LIG4, XRCC5, DDIT3, MSH2, ERCC5, RPA3, POLD1), and in apoptosis (PARP).
    In vivo:
    Nat Prod Res. 2013;27(17):1569-75.
    Betula pendula Roth leaves: gastroprotective effects of an HPLC-fingerprinted methanolic extract.[Pubmed: 23163340]
    In this study, a methanolic extract of Betula pendula leaves (BLE) was investigated for its gastroprotective effects against 90% ethanol-induced ulcer in rats.
    METHODS AND RESULTS:
    Oral pretreatment of rats with BLE (100, 200 and 400 mg kg(- 1)) significantly reduced the incidence of gastric lesions induced by ethanol administration as compared with misoprostol (0.50 mg kg(- 1)). Furthermore, BLE inhibited the increase in malondialdehyde (MDA) and prevented depletion of total sulhydryl and non-protein sulhydryl groups in rat stomach homogenate when compared with ethanol group. With regard to the effect of lipid peroxidation in vitro, BLE showed the ability to reduce methyl linoleate autoxidation.
    CONCLUSIONS:
    Chemical characterisation of the main biologically active constituents of BLE was also achieved by means of high-performance liquid chromatography with photodiode array and mass spectrometry detection, showing the presence of Myricetin 3-O-galactoside, quercetin glycosides, kaempferol glycosides.
    Asian Journal of Plant Sciences, 2012, 11(3): 124-30.
    Cytotoxicity and Suppressive Effect of Leaves of Mimusops laurifolia on Carbon Tetrachloride-induced Liver Injury in Rats and its Bioactive Constituents[Reference: WebLink]
    Since the genus Mimusops is one of the important genera in the Indian traditional medicine, and is represented in Egypt with species; Mimusops laurifolia (Forssk.) Friis., thus the plant is selected for our investigation to reveal its biological activities and phytochemically analyze its bioactive fractions.
    METHODS AND RESULTS:
    The ethanolic extract of its leaves (LEE) and its different fractions: n-hexane (HF), chloroform (CF), ethyl acetate (EAF) and n-butanol (BF) were evaluated for in vivo hepatoprotective activity against CC14 induced hepatic cell damage in rats and for in vitro cytotoxicity against human liver cancer cell line (HEPG2); consequently the bioactive constituents were defined whereby EAF evidenced statistically significant hepatoprotection. Moreover, HF and α-amyrin (major compound isolated from HF) showed promising cytotoxicity against HEPG2. Structures of isolated compounds were established on the basis of physicochemical properties and spectral analysis. The bioactive fractions were examined for the isolation of 14 compounds for the first time from Mimusops laurifolia (Forssk.) Friis. From the lipophilic fractions: Lupeol acetate, α-amyrin, chondrillasterol, oleanolic acid, chondr111 asterol-3-O-β-D-galactoside, meamsitrin, myricetin and quercetin were isolated. While, from EAF: mearnsitrin, myricitrin, myricetin- 3 - O -β-D -g alactoside(Myricetin 3-O-galactoside), quercetin- 3 - O - β-D-g lucoside, rutin and myncetin-3-0-β- D-glucuronide were isolated.
    CONCLUSIONS:
    Leaves of Mimusops laurifolia (Forssk.) Friis can be considered as a natural medicinal plant with a potential anticancer and hepatoprotection due to its bioactive ingredients in both HF and EAF, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0817 mL 10.4084 mL 20.8169 mL 41.6337 mL 52.0421 mL
    5 mM 0.4163 mL 2.0817 mL 4.1634 mL 8.3267 mL 10.4084 mL
    10 mM 0.2082 mL 1.0408 mL 2.0817 mL 4.1634 mL 5.2042 mL
    50 mM 0.0416 mL 0.2082 mL 0.4163 mL 0.8327 mL 1.0408 mL
    100 mM 0.0208 mL 0.1041 mL 0.2082 mL 0.4163 mL 0.5204 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    杨梅素-3-O-β-D-木糖(1-2)-β-D-葡萄糖苷; Myricetin 3-O-beta-D-xylopyranosyl(1-2)-beta-D-glucopyranoside CFN80126 142449-93-2 C26H28O17 = 612.13 5mg QQ客服:2159513211
    杨梅素-3-O-β-D-木糖(1-2)-[α-L-鼠李糖-(1-6)]-β-D-葡萄糖苷; Myricetin 3-O-beta-D-xylopyranosyl(1-2)-[alpha-L-rhamnopyranosyl-(1-6)]-beta-D-glucopyranoside CFN80330 N/A C32H38O21 = 758.63 5mg QQ客服:2159513211
    杨梅素-3'-O-β-D-葡萄糖苷; Cannabiscitrin CFN95278 520-14-9 C21H20O13 = 480.4 5mg QQ客服:3257982914
    沙苑子苷A; Complanatoside A CFN99525 146501-37-3 C27H30O18 = 642.5 5mg QQ客服:3257982914
    杨梅酮 4'-甲醚-3-O-鼠李糖苷; Mearnsitrin CFN98387 30484-88-9 C22H22O12 = 478.4 5mg QQ客服:3257982914
    落叶黄素-3-O-β-D-葡萄糖苷; Laricitrin 3-O-glucoside CFN80175 39986-90-8 C22H22O13 = 494.10 5mg QQ客服:3257982914
    丁香亭-3-O-葡糖苷; Syringetin-3-O-glucoside CFN90468 40039-49-4 C23H24O13 = 508.43 5mg QQ客服:215959384
    丁香亭-3-O-半乳糖苷; Syringetin 3-O-galactoside CFN70408 55025-56-4 C23H24O13 = 508.4 5mg QQ客服:2159513211
    丁香亭-3-O-芸香糖苷; Syringetin-3-O-rutinoside CFN91150 53430-50-5 C29H34O17 = 654.6 5mg QQ客服:1413575084
    杨梅苷; 五羟基黄酮-3-鼠李糖苷; Myricitrin CFN99840 17912-87-7 C21H20O12 = 464.4 20mg QQ客服:215959384

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