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  • 2alpha,3alpha,19alpha,23-四羟基乌苏-12-烯-28-酸

    Myrianthic acid

    2alpha,3alpha,19alpha,23-四羟基乌苏-12-烯-28-酸
    产品编号 CFN96828
    CAS编号 89786-84-5
    分子式 = 分子量 C30H48O6 = 504.70
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The stems of Poraqueiba sericea.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    2alpha,3alpha,19alpha,23-四羟基乌苏-12-烯-28-酸 CFN96828 89786-84-5 1mg QQ客服:1457312923
    2alpha,3alpha,19alpha,23-四羟基乌苏-12-烯-28-酸 CFN96828 89786-84-5 5mg QQ客服:1457312923
    2alpha,3alpha,19alpha,23-四羟基乌苏-12-烯-28-酸 CFN96828 89786-84-5 10mg QQ客服:1457312923
    2alpha,3alpha,19alpha,23-四羟基乌苏-12-烯-28-酸 CFN96828 89786-84-5 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Lodz (Poland)
  • Wageningen University (Netherlands)
  • Uniwersytet Jagielloński w Krakowie (Poland)
  • Chiang Mai University (Thailand)
  • Kyung Hee University (Korea)
  • Georgia Institute of Technology (USA)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • University of Malaya (Malaysia)
  • Universiti Putra Malaysia(UPM) (Malaysia)
  • Indian Institute of Science (India)
  • Lund University (Sweden)
  • MTT Agrifood Research Finland (Finland)
  • Kitasato University (Japan)
  • Pennsylvania State University (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • LWT2021, 138:110630.
  • J of L. Chroma.&Related Tech2017, 252-258
  • Molecules.2022, 27(21):7643.
  • J of the Korean Society of Food Science and Nutrition2016, 45(7):1017-1025
  • Phytother Res.2015, 29(7):1088-96
  • Appl. Sci.2023, 13(17), 9653.
  • Kaohsiung J Med Sci.2023, 10.1002/kjm2.12764
  • Tropical J. of Pha. Research2017, 16(3):543-552
  • Biomolecules.2023, 13(2):227.
  • The Korea Journal of Herbology2016, 29-35
  • J Ginseng Res.2020, 44(4):611-618.
  • Front Cell Dev Biol.2021, 9:764263.
  • J of l. Chroma.&Related Tech2020, 43(11-12):414-423.
  • J Cell Physiol.2021, 236(3):1950-1966.
  • J Ethnopharmacol.2020, 260:112988.
  • J Cell Physiol.2020, 10.1002
  • J Insect Sci.2020, 20(5):18.
  • J Am Soc Mass Spectrom.2021, 32(9):2451-2462.
  • Evid Based Complement Alternat Med.2017, 2017:1583185
  • J Appl Biol Chem2022, 65:343−348.
  • Int J Mol Sci.2015, 16(8):18396-411
  • Nutrients.2022, 14(19):4170.
  • University of Limpopo2016, 1777
  • ...
  • 生物活性
    Description: Myrianthic acid shows anticancer activity, it shows inhibitory activities on foam cell formation in human monocyte-derived macrophages induced by acetylated low-density lipoproteins at a 50 uM concentration. Myrianthic acid is equivalently inhibitive as acetylsalicylic acid (IC50: 57.0 microM) on epinephrine induced platelet aggregation.
    Targets: AChR | PAFR
    In vitro:
    Nat Prod Res. 2017 Jun;31(11):1333-1338.
    Biological activities of triterpenoids from Poraqueiba sericea stems.[Pubmed: 27736194]
    Eleven compounds were isolated from Poraqueiba sericea stems and identified as niga-ichigoside-F1 (1), trachelosperoside B1 (2), 4-epi-niga-ichigoside (7), 19α-hydroxyasiatic acid (3), myrianthic acid (4), hyptatic acid (5), trachelosperogenin B (6), arjunolic acid (8), and trachelosperogenin E (9), secologanoside (10) and secoxyloganin (11).
    METHODS AND RESULTS:
    Compounds 1-11 were tested for their antileishmanial activities against Leishmania infantum promastigotes, 1-6 and 8-11 were tested for their cytotoxic activities on fibroblasts, 1-3, 5-6, 8-11 were evaluated for their anti-elastase and anti-acetylcholinesterase assays activities by a spectrophotometric method and 1-2, 5 and 7-10 were tested using bioautography for their β-glucosidase.
    CONCLUSIONS:
    No antileishmanial activity was detected; compounds 1, 2 and 11 showed a moderate cytotoxic activity with IC50 17.7, 20.5 and 10.9 μg/mL, respectively; compounds 2, 8, 9 and 10 gave a percentage of inhibition ranging from 13 to 16% (at 50 μg/mL) and compounds 1 and 2 showed an inhibition zone on β-glucosidase and anti-acetylcholinesterase assays.
    Zhongguo Zhong Yao Za Zhi. 2006 Nov;31(22):1875-9.
    Triterpenes from herb of Potentilla chinesis.[Pubmed: 17285988]

    METHODS AND RESULTS:
    Five pentacyclic triterpenoids, oleanolic acid (1), hederagenin (2), ursolic acid (3), tormentic acid (4) and myrianthic acid (5), were isolated from the methanol extract of the leaves of Campsis grandiflora, and structures of the compounds were established by the spectroscopic methods. Compounds 2, 3, 4, and 5 were isolated for the first time from the genus Campsis.
    CONCLUSIONS:
    All of the compounds (IC50: 45.3, 32.8, 82.6, 42.9 and 46.2 microM respectively) were as equivalently inhibitive as acetylsalicylic acid (IC50: 57.0 microM) on epinephrine induced platelet aggregation.
    Arch Pharm Res. 2004 Apr;27(4):376-80.
    Anti-platelet pentacyclic triterpenoids from leaves of Campsis grandiflora.[Pubmed: 15180300]

    METHODS AND RESULTS:
    Five pentacyclic triterpenoids, oleanolic acid (1), hederagenin (2), ursolic acid (3), tormentic acid (4) and myrianthic acid (5), were isolated from the methanol extract of the leaves of Campsis grandiflora, and structures of the compounds were established by the spectroscopic methods. Compounds 2, 3, 4, and 5 were isolated for the first time from the genus Campsis.
    CONCLUSIONS:
    All of the compounds (IC50: 45.3, 32.8, 82.6, 42.9 and 46.2 microM respectively) were as equivalently inhibitive as acetylsalicylic acid (IC50: 57.0 microM) on epinephrine induced platelet aggregation.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.9814 mL 9.9069 mL 19.8138 mL 39.6275 mL 49.5344 mL
    5 mM 0.3963 mL 1.9814 mL 3.9628 mL 7.9255 mL 9.9069 mL
    10 mM 0.1981 mL 0.9907 mL 1.9814 mL 3.9628 mL 4.9534 mL
    50 mM 0.0396 mL 0.1981 mL 0.3963 mL 0.7926 mL 0.9907 mL
    100 mM 0.0198 mL 0.0991 mL 0.1981 mL 0.3963 mL 0.4953 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    马尾柴酸; Barbinervic acid CFN96162 64199-78-6 C30H48O5 = 488.7 5mg QQ客服:2056216494
    2alpha,3alpha,19alpha,23-四羟基乌苏-12-烯-28-酸 ; Myrianthic acid CFN96828 89786-84-5 C30H48O6 = 504.70 5mg QQ客服:215959384
    19 alpha-Hydroxyasiatic acid; 19 alpha-Hydroxyasiatic acid CFN91072 70868-78-9 C30H48O6 = 504.7 10mg QQ客服:215959384
    Myrianthic acid 3,23-acetonide; Myrianthic acid 3,23-acetonide CFN89232 578710-52-8 C33H52O6 = 544.77 5mg QQ客服:1457312923
    去羟加利果酸; Esculentic acid CFN99059 103974-74-9 C30H48O5 = 488.7 5mg QQ客服:2056216494
    (2ALPHA,3BETA,4ALPHA)-2,3,23-三羟基乌苏-12,20(30)-二烯-28-酸; Actinidic acid CFN98444 341971-45-7 C30H46O5 = 486.7 5mg QQ客服:2056216494
    积雪草酸; Asiatic acid CFN98688 464-92-6 C30H48O5 = 488.7 20mg QQ客服:1413575084
    3-O-香豆酰积雪草酸; 3-O-Coumaroylasiatic acid CFN96830 143773-52-8 C39H54O7 = 634.85 5mg QQ客服:2159513211
    积雪草苷; Asiaticoside CFN99912 16830-15-2 C48H78O19 = 959.12 20mg QQ客服:3257982914
    羟基积雪草苷; Madecassoside CFN99913 34540-22-2 C48H78O20 = 975.13 20mg QQ客服:1413575084

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