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  • 甲基丁香酚, 甲基丁子香酚

    • 甲基丁香酚, 甲基丁子香酚

    Methyleugenol

    甲基丁香酚, 甲基丁子香酚
    		产品编号 CFN96177
    CAS编号 93-15-2
    分子式 = 分子量 C11H14O2 = 178.2
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Phenylpropanoids
    植物来源 The herbs of Syringa Linn.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    甲基丁香酚, 甲基丁子香酚 CFN96177 93-15-2 10mg QQ客服：2056216494
    甲基丁香酚, 甲基丁子香酚 CFN96177 93-15-2 20mg QQ客服：2056216494
    甲基丁香酚, 甲基丁子香酚 CFN96177 93-15-2 50mg QQ客服：2056216494
    甲基丁香酚, 甲基丁子香酚 CFN96177 93-15-2 100mg QQ客服：2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
  • Universidade do Porto (Portugal)
  • Melbourne University (Australia)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • University of Amsterdam (Netherlands)
  • Universidade Católica Portuguesa (Portugal)
  • Copenhagen University (Denmark)
  • Universidade Federal de Goias (UFG) (Brazil)
  • University of Leipzig (Germany)
  • Vin?a Institute of Nuclear Sciences (Serbia)
  • Institute of Chinese Materia Medica (China)
  • The Institute of Cancer Research (United Kingdom)
  • University of Bordeaux (France)
  • University of Padjajaran (Indonesia)
  • Universidad de Antioquia (Colombia)
  • More...
    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Molecules2021, 26(1),230
  • Int. J of Herbal Med.2023, 11(1): 06-14
  • Biorxiv2019, 10.1101
  • Food Chem.2020, 332:127412
  • Kangwon National University2022, 37(1):29-37
  • Int J Mol Sci.2022, 23(10):5468.
  • J Sep Sci.2018, 41(11):2488-2497
  • Food Science and Biotechnology2022, 10.1007.
  • Int J Mol Sci.2022, 23(15):8687.
  • Food Funct.2022, 13(13):6923-6933.
  • Front Pharmacol.2021, 12:770667.
  • J Nat Prod.2022, 85(5):1351-1362.
  • J Med Food.2021, 24(2):151-160.
  • J Cell Mol Med.2020, 24(21):12308-12317.
  • J. Soc. Cosmet. Sci. Korea2016, 163-171
  • Industrial Food Engineering2015, 19(4):408-413
  • Biomed Pharmacother.2022, 156:113929.
  • The Journal of Agromedicine and Medical Sciences2018, 4(1)
  • Food Research International2023, 113792.
  • Front Pharmacol.2016, 7:460
  • Heliyon.2023, 9:e21652.
  • Evid Based Complement Alternat Med.2022, 9767292,2.
  • Anal Chim Acta.2018, 1039:162-171
  • ...
    • 生物活性
    Description: Methyleugenol (ME) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of ME, the need to check its presence in food products with effective analytical methods. ME has elaxant and antispasmodic actions on guinea-pig isolated ileum, it also has antinociceptive, anti-inflammatory, and insecticidal properties.ME can inhibit the production of nitric oxide and decreased the protein expression of inducible nitric oxide synthase, it down-regulates the production of pro-inflammatory cytokines in the ischemic brain as well as in immunostimulated mixed glial cells.
    Targets: NOS | NMDAR | Caspase | COX | GABA Receptor
    In vivo:
    Free Radical. Res., 2010, 44(8):925-35.
    Methyleugenol reduces cerebral ischemic injury by suppression of oxidative injury and inflammation.[Pubmed: 20815773 ]

    METHODS AND RESULTS:
    The present study tested the cytoprotective effect of methyleugenol in an in vivo ischemia model (i.e. middle cerebral artery occlusion (MCAO) for 1.5 h and subsequent reperfusion for 24 h) and further investigated its mechanism of action in in vitro cerebral ischemic models. When applied shortly after reperfusion, methyleugenol largely reduced cerebral ischemic injury. Methyleugenol decreased the caspase-3 activation and death of cultured cerebral cortical neurons caused by oxygen-glucose deprivation (OGD) for 1 h and subsequent re-oxygenation for 24 h. Methyleugenol markedly reduced superoxide generation in the ischemic brain and decreased the intracellular oxidative stress caused by OGD/re-oxygenation. It was found that methyleugenol elevated the activities of superoxide dismutase and catalase. Further, methyleugenol inhibited the production of nitric oxide and decreased the protein expression of inducible nitric oxide synthase. Methyleugenol down-regulated the production of pro-inflammatory cytokines in the ischemic brain as well as in immunostimulated mixed glial cells.
    CONCLUSIONS:
    The results indicate that methyleugenol could be useful for the treatment of ischemia/inflammation-related diseases.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.6117 mL 28.0584 mL 56.1167 mL 112.2334 mL 140.2918 mL
    5 mM 1.1223 mL 5.6117 mL 11.2233 mL 22.4467 mL 28.0584 mL
    10 mM 0.5612 mL 2.8058 mL 5.6117 mL 11.2233 mL 14.0292 mL
    50 mM 0.1122 mL 0.5612 mL 1.1223 mL 2.2447 mL 2.8058 mL
    100 mM 0.0561 mL 0.2806 mL 0.5612 mL 1.1223 mL 1.4029 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    5-烯丙基-1,2,3-三甲氧基苯; Elemicin CFN90685 487-11-6 C12H16O3 = 208.3 20mg QQ客服：1457312923
    肉豆蔻醚; Myristicin CFN90589 607-91-0 C11H12O3 = 192.21 5mg QQ客服：215959384
    芹菜脑; Apioline CFN70479 523-80-8 C12H14O4 = 222.2 20mg QQ客服：3257982914
    α-细辛脑; alpha-Asarone CFN93217 2883-98-9 C12H16O3 = 208.25 20mg QQ客服：1457312923
    (Z)-1,2,4-三甲氧基-5- 丙烯基苯; 顺式细辛脑; beta-Asarone CFN98870 5273-86-9 C12H16O3 = 208.3 5mg QQ客服：3257982914
    赤式-1',2'-二羟基细辛醚; Erythro-1',2'-dihydroxyasarone CFN95655 146830-05-9 C12H18O5 = 242.3 5mg QQ客服：1413575084
    苏式-1',2'-二羟基细辛醚; Threo-1',2'-dihydroxyasarone CFN95656 N/A C12H18O5 = 242.3 10mg QQ客服：215959384
    茴香脑; Anethole CFN98550 104-46-1 C10H12O = 148.2 20mg QQ客服：2159513211
    4-烯丙基儿茶酚; 4-(2-丙烯基)-1,2-苯二醇; 4-烯丙基-1,2-苯二醇; 4-Allylpyrocatechol CFN99226 1126-61-0 C9H10O2 = 150.2 20mg QQ客服：2159513211
    丁香酚; Eugenol CFN99175 97-53-0 C10H12O2 = 164.20 20mg QQ客服：2159513211

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