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  • 水杨酸甲酯

    Methyl salicylate

    水杨酸甲酯
    产品编号 CFN98549
    CAS编号 119-36-8
    分子式 = 分子量 C8H8O3 = 152.15
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Phenols
    植物来源 The leaves of Cassia acutifolia Delile
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
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    水杨酸甲酯 CFN98549 119-36-8 10mg QQ客服:2932563308
    水杨酸甲酯 CFN98549 119-36-8 20mg QQ客服:2932563308
    水杨酸甲酯 CFN98549 119-36-8 50mg QQ客服:2932563308
    水杨酸甲酯 CFN98549 119-36-8 100mg QQ客服:2932563308
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Aveiro University (Portugal)
  • Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)
  • Yale University (USA)
  • Charles Sturt University (Denmark)
  • Subang Jaya Medical Centre (Malaysia)
  • Universitas Airlangga (Indonesia)
  • Universidade do Porto (Portugal)
  • Calcutta University (India)
  • University of Amsterdam (Netherlands)
  • University of Virginia (USA)
  • Shanghai Institute of Organic Chemistry (China)
  • Leibniz Institute of Plant Biochemistry (Germany)
  • The Ohio State University (USA)
  • Chinese University of Hong Kong (China)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Eur J Pharm Sci.2016, 94:33-45
  • PLoS One.2017, 12(3):e0173585
  • Exp Parasitol.2017, 183:160-166
  • Evid Based Complement Alternat Med.2017, 2017:6360836
  • Int J Mol Sci.2018, 19(9):E2825
  • The Journal of Agromedicine and Medical Sciences2018, 4(1)
  • Sci Rep. 2018, 462(8)
  • Biochem Biophys Res Commun.2018, 495(1):1271-1277
  • Journal of Life Science2018, 917-922
  • J Sci Food Agric.2018, 98(3):1153-1161
  • Chemistry of Plant Materials.2019, 129-136
  • Food Engineering Progress2019, 23(3)209-216
  • Molecules.2019, 24(12):E2286
  • Molecules.2019, 24(23):E4303
  • Phytother Res.2019, 33(4):1104-1113
  • FASEB J.2019, 33(8):9685-9694
  • Journal of Food Hygiene and Safety2019, 34(5):413-420
  • J Food Sci Technol.2019, 56(5):2712-2720
  • Plos One.2019, 15(2):e0220084
  • Pharmacol Rep.2019, 71(2):289-298
  • Biomolecules.2019, 9(11):E696
  • J of Applied Pharmaceutical Science2020, 10(1):077-082
  • Plant Growth Regulation2020, 90(2):383-392
  • ...
  • 生物活性
    Description: Methyl salicylate is a common herbivore-induced plant volatile that, when applied to crops, has the potential to enhance natural enemy abundance and pest control. Methyl salicylate has both stimulatory and inhibitory actions on TRPV1 channels, it shows analgesic effects.
    Targets: Estrogen receptor | NF-kB | TNF-α | Progestogen receptor
    In vitro:
    Environ Microbiol. 2015 Apr;17(4):1365-76.
    Plant methyl salicylate induces defense responses in the rhizobacterium Bacillus subtilis.[Pubmed: 25181478]
    Bacillus subtilis is a rhizobacterium that promotes plant growth and health. Cultivation of B. subtilis with an uprooted weed on solid medium produced pleat-like architectures on colonies near the plant. To test whether plants emit signals that affect B. subtilis colony morphology, we examined the effect of plant-related compounds on colony morphology.
    METHODS AND RESULTS:
    Bacillus subtilis formed mucoid colonies specifically in response to methyl salicylate, which is a plant-defense signal released in response to pathogen infection. Methyl salicylate induced mucoid colony formation by stimulating poly-γ-glutamic acid biosynthesis, which formed enclosing capsules that protected the cells from exposure to antimicrobial compounds. Poly-γ-glutamic acid synthesis depended on the DegS-DegU two-component regulatory system, which activated DegSU-dependent gene transcription in response to methyl salicylate. Bacillus subtilis did not induce plant methyl salicylate production, indicating that the most probable source of methyl salicylate in the rhizosphere is pathogen-infected plants. Methyl salicylate induced B. subtilis biosynthesis of the antibiotics bacilysin and fengycin, the latter of which exhibited inhibitory activity against the plant pathogenic fungus Fusarium oxysporum.
    CONCLUSIONS:
    We propose that B. subtilis may sense plants under pathogen attack via methyl salicylate, and express defense responses that protect both B. subtilis and host plants in the rhizosphere.
    Drug Test Anal. 2014 Jun;6 Suppl 1:67-73.
    Hair analysis as a useful procedure for detection of vapour exposure to chemical warfare agents: simulation of sulphur mustard with methyl salicylate.[Pubmed: 24817050 ]
    Chemical warfare agents (CWA) are highly toxic compounds which have been produced to kill or hurt people during conflicts or terrorist attacks. Despite the fact that their use is strictly prohibited according to international convention, populations' exposure still recently occurred. Development of markers of exposure to CWA is necessary to distinguish exposed victims from unexposed ones.
    METHODS AND RESULTS:
    We present the first study of hair usage as passive sampler to assess contamination by chemicals in vapour form. This work presents more particularly the hair adsorption capacity for methyl salicylate used as a surrogate of the vesicant sulphur mustard. Chemical vapours toxicity through the respiratory route has historically been defined through Haber's law's concentration-time (Ct) product, and vapour exposure of hair to methyl salicylate was conducted with various times or doses of exposure in the range of incapacitating and lethal Ct products corresponding to sulphur mustard. Following exposure, extraction of methyl salicylate from hair was conducted by simple soaking in dichloromethane. Methyl salicylate could be detected on hair for vapour concentration corresponding to about one fifth of the sulphur mustard concentration that would kill 50% of exposed individuals (LCt50). The amount of methyl salicylate recovered from hair increased with time or dose of exposure.
    CONCLUSIONS:
    It showed a good correlation with the concentration-time product, suggesting that hair could be used like a passive sampler to assess vapour exposure to chemical compounds. It introduces great perspectives concerning the use of hair as a marker of exposure to CWA.
    J Am Mosq Control Assoc. 2014 Sep;30(3):199-203.
    Fumigant Activity of 6 Selected Essential Oil Compounds and Combined Effect of Methyl Salicylate And Trans-Cinnamaldehyde Against Culex pipiens pallens.[Pubmed: 25843095]
    We studied the knockdown activity and lethal toxicity of 6 essential oil compounds-methyl salicylate, linalool, 2-phenethyl alcohol, eugenol, β-citronellol, and trans-cinnamaldehyde-as fumigants against adult female Culex pipiens pallens in the laboratory.
    METHODS AND RESULTS:
    Of the 6 products tested, trans-cinnamaldehyde was the most toxic (LC50  =  0.26 μl/l air, 24 h) with a slow knockdown time (KT95  =  176.5 min at 0.5 μl/l air). Methyl salicylate displayed a lower toxicity (LC50  =  1.17 μl/l air, 24 h) but the fastest knockdown activity (KT95  =  16.8 min) at the sublethal concentration 0.5 μl/l air. Furthermore, the binary mixture of methyl salicylate and trans-cinnamaldehyde exhibited a combined effect of fast knockdown activity and high toxicity against Cx. p. pallens adults, showing potential for development as natural fumigants for mosquito control.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 6.5725 mL 32.8623 mL 65.7246 mL 131.4492 mL 164.3115 mL
    5 mM 1.3145 mL 6.5725 mL 13.1449 mL 26.2898 mL 32.8623 mL
    10 mM 0.6572 mL 3.2862 mL 6.5725 mL 13.1449 mL 16.4312 mL
    50 mM 0.1314 mL 0.6572 mL 1.3145 mL 2.629 mL 3.2862 mL
    100 mM 0.0657 mL 0.3286 mL 0.6572 mL 1.3145 mL 1.6431 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    水杨酸甲酯; Methyl salicylate CFN98549 119-36-8 C8H8O3 = 152.15 20mg QQ客服:1413575084
    2,6-二羟基苯甲酸甲酯; Methyl 2,6-dihydroxybenzoate CFN92655 2150-45-0 C8H8O4 = 168.2 20mg QQ客服:2932563308
    6-(beta-D-吡喃葡萄糖氧基)水杨酸甲酯; 6-(beta-D-glucopyranosyloxy)-Salicylic acid methyl ester CFN99087 108124-75-0 C14H18O9 = 330.3 5mg QQ客服:2932563308
    2,6-二甲氧基苯甲酸; 2,6-Dimethoxybenzoic acid CFN99607 1466-76-8 C9H10O4 = 182.2 20mg QQ客服:3257982914
    Benzyl 2,6-dimethoxybenzoate; Benzyl 2,6-dimethoxybenzoate CFN92793 34328-54-6 C16H16O4 = 272.3 5mg QQ客服:1148253675
    2,4-二羟基苯乙酸甲酯; Methyl 2,4-dihydroxyphenylacetate CFN96486 67828-42-6 C9H10O4 = 182.17 5mg QQ客服:2932563308
    2’,4’-二羟基-6’-甲氧基苯乙酮; 2',4'-Dihydroxy-6'-methoxyacetophenone CFN98488 3602-54-8 C9H10O4 = 182.2 5mg QQ客服:2932563308
    Ethyl 2,4,6-trihydroxybenzoate; Ethyl 2,4,6-trihydroxybenzoate CFN96091 90536-74-6 C9H10O5 = 198.2 5mg QQ客服:2159513211

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