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  • 氯化锦葵色素-3-O-半乳糖苷

    • 氯化锦葵色素-3-O-半乳糖苷

    Malvidin-3-O-galactoside chloride

    氯化锦葵色素-3-O-半乳糖苷
    		产品编号 CFN92048
    CAS编号 30113-37-2
    分子式 = 分子量 C23H25ClO12 = 528.9
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The fruits of Vaccinium myrtillus
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    氯化锦葵色素-3-O-半乳糖苷 CFN92048 30113-37-2 1mg QQ客服：2159513211
    氯化锦葵色素-3-O-半乳糖苷 CFN92048 30113-37-2 5mg QQ客服：2159513211
    氯化锦葵色素-3-O-半乳糖苷 CFN92048 30113-37-2 10mg QQ客服：2159513211
    氯化锦葵色素-3-O-半乳糖苷 CFN92048 30113-37-2 20mg QQ客服：2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
  • Washington State University (USA)
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  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • Auburn University (USA)
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    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Immunol.2023, ji2200727.
  • LWT2021, 138:110397.
  • Biomedicines.2022, 10(2):463.
  • Int J Pharm.2022, 618:121636.
  • J Chromatogr B Analyt Technol Biomed Life Sci.2021, 1187:123012.
  • J Pharm Biomed Anal.2018, 151:32-41
  • bioRxiv - Biochemistry2023, 548213.
  • J Chromatogr B Analyt Technol Biomed Life Sci.2022, 1203:123307.
  • Molecules.2019, 24(1):E159
  • Biosci Biotechnol Biochem.2021, 85(10):2153-2160.
  • Food Addit Contam Part A.2021, 38(12):1985-1994.
  • Applied Biological Chemistry 2022, 65,5(2022).
  • Food Research2021, 5(1):65-71
  • Phytomedicine.2020, 153440.
  • Pharmacol Rep.2017, 69(6):1224-1231
  • Research Square2022, rs.3.rs-1948239
  • ACS Omega.2021, 6(36):23460-23474.
  • Molecules.2021, 26(23):7390.
  • Universite de Bordeaux2017, 2017BORD0867
  • Drug Test Anal.2018, 10(10):1579-1589
  • Hum Exp Toxicol.2017, 36(11):1169-1176
  • Chinese Journal of Hospital Pharmacy2020, 40(7)
  • Food Sci Biotechnol.2023, 32(7):997-1003.
  • ...
    • 生物活性
    Description: Malvidin-3-O-galactoside chloride has antioxidant activity.
    In vitro:
    Food Funct. 2015 Mar 11;6(3):772-9.
    Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes.[Pubmed: 25578040]
    Anthocyans (anthocyanins and their aglycones anthocyanidins) are colorful pigments, naturally occurring in fruits. They exhibit many biological effects and have potent health benefits. Anthocyans are widely used as dietary supplements and the safety of products containing them is of great importance. To investigate whether anthocyans influence the expression of hepatic uptake transporters from the organic anion transporting polypeptide (SLCO gene/OATP protein) family, we carried out studies on primary cultures of human hepatocytes.
    METHODS AND RESULTS:
    The hepato-cellular accumulation of widely used drugs such as statins and some anticancer drugs is mediated by the liver-specific OATP1B1 and OATP1B3, thus any interference with expression of these particular transporters might influence therapeutic outcomes. We evaluated the effects of 21 anthocyanins and their corresponding 6 anthocyanidins on the expression levels of SLCO1B1/SLCO1B3 by RT-qPCR. Changes in OATP protein levels were confirmed by western blotting. Our data show that OATP1B1 responds differently to anthocyans compared with OATP1B3. We observed the induction of SLCO1B1 gene and OATP1B1 protein in four hepatocyte samples by the anthocyanins malvin chloride, Malvidin-3-O-galactoside chloride and cyanidin-3-O-sophoroside chloride. For SLCO1B3, a reduction in the expression levels was seen with delphin chloride and the anthocyanidin pelargonidin. Although the values varied considerably between primary hepatocyte isolates from different individuals, a mean induction of SLCO1B1 (up to 60%) and reduction of SLCO1B3 (by less than 25%) were detected.
    CONCLUSIONS:
    We propose that the effects of anthocyans derived from high dose dietary supplements may have to be taken into account in patients undergoing a therapy with drugs transported by OATP1B1 and OATP1B3.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8907 mL 9.4536 mL 18.9072 mL 37.8143 mL 47.2679 mL
    5 mM 0.3781 mL 1.8907 mL 3.7814 mL 7.5629 mL 9.4536 mL
    10 mM 0.1891 mL 0.9454 mL 1.8907 mL 3.7814 mL 4.7268 mL
    50 mM 0.0378 mL 0.1891 mL 0.3781 mL 0.7563 mL 0.9454 mL
    100 mM 0.0189 mL 0.0945 mL 0.1891 mL 0.3781 mL 0.4727 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    氯化芍药素-3-O-阿拉伯糖苷; Peonidin-3-O-arabinoside chloride CFN92047 524943-91-7 C21H21ClO10 = 468.8 5mg QQ客服：3257982914
    氯化芍药素-3-O-半乳糖苷; Peonidin-3-O-galactoside chloride CFN92045 28148-89-2 C22H23ClO11 = 498.9 5mg QQ客服：1413575084
    氯化芍药素-3-O-葡萄糖苷; Peonidin-3-O-glucoside chloride CFN92046 6906-39-4 C22H23ClO11 = 498.9 5mg QQ客服：2056216494
    氯化芍药素-3,5-O-双葡萄糖苷; Peonidin-3,5-O-diglucoside chloride CFN91868 132-37-6 C28H33ClO16 = 661.0 5mg QQ客服：215959384
    = 5mg QQ客服：3257982914
    氯化失车菊素-3-O-葡萄糖苷; Cyanidin-3-O-glucoside chloride CFN99740 7084-24-4 C21H21O11 = 449.38 20mg QQ客服：3257982914
    氯化矢车菊素-3-O-阿拉伯糖苷; Cyanidin-3-O-arabinoside chloride CFN92041 111613-04-8 C20H19ClO10 = 454.8 10mg QQ客服：1457312923
    氯化失车菊素-3-O-半乳糖苷; Cyanidin-3-O-galactoside chloride CFN92040 27661-36-5 C21H21ClO11 = 484.9 10mg QQ客服：1413575084
    氯化失车菊素-3-O-桑布双糖苷; Cyanidin-3-O-sambubioside chloride CFN92173 33012-73-6 C26H29ClO15 = 617.0 10mg QQ客服：2159513211
    矢车菊素-3-O-桑布双糖苷-5-O-葡萄糖苷; Cyanidin-3-O-sambubioside-5-O-glucoside chloride CFN91865 53925-33-0 C32H39ClO20 = 779.1 10mg QQ客服：1413575084

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