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  • 6-甲氧基香豆素-7-0-beta-D-吡喃葡萄糖苷

    Magnolioside

    6-甲氧基香豆素-7-0-beta-D-吡喃葡萄糖苷
    产品编号 CFN90699
    CAS编号 20186-29-2
    分子式 = 分子量 C16H18O9 = 354.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Coumarins
    植物来源 The herbs of Artemisia scoparia.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    6-甲氧基香豆素-7-0-beta-D-吡喃葡萄糖苷 CFN90699 20186-29-2 1mg QQ客服:2159513211
    6-甲氧基香豆素-7-0-beta-D-吡喃葡萄糖苷 CFN90699 20186-29-2 5mg QQ客服:2159513211
    6-甲氧基香豆素-7-0-beta-D-吡喃葡萄糖苷 CFN90699 20186-29-2 10mg QQ客服:2159513211
    6-甲氧基香豆素-7-0-beta-D-吡喃葡萄糖苷 CFN90699 20186-29-2 20mg QQ客服:2159513211
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
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    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

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  • PLoS One.2021, 16(9):e0257243.
  • Biomolecules.2021, 11(10):1537.
  • J Med Food.2021, 24(2):151-160.
  • Front Pharmacol.2021, 12:615157.
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  • Food Structure2023, 36:100324.
  • Nat Prod Commun.2014, 9(5):679-82
  • J Ethnopharmacol.2017, 198:87-90
  • Am J Chin Med.2015, 30:1-22
  • Oncol Lett.2020, 20(4):122.
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  • Phytomedicine.2023, 117:154929.
  • ACS Nano.2018, 12(4):3385-3396
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  • J.of Traditional&Complementary Med.2022, 10.1016:j.jtcme.
  • Front Pharmacol.2022, 13:806869.
  • Phytochemistry.2021, 181:112539.
  • Chinese Journal of Hospital Pharmacy2020, 40(7)
  • Pharmaceutical Chemistry Journal2019, 52(12):986-991
  • ...
  • 生物活性
    Description: Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a moderate antibacterial activity against Staphylococcus aureus CIP 53.154.
    Targets: Antifection
    In vitro:
    Immunopharmacol Immunotoxicol. 2011 Dec;33(4):663-6.
    Antiplasmodial and cytotoxic activity of coumarin derivatives from dried roots of Angelica gigas Nakai in vitro.[Pubmed: 21428713]
    The butanol-soluble fraction of the dried root of Angelica gigas exhibited significant protection against chloroquine-sensitive strains of Plasmodium falciparum using the parasite lactate dehydrogenase assay method.
    METHODS AND RESULTS:
    Using antiplasmodial activity-guided fractionation, five coumarins, marmesinin (1), nodakenin (2), skimmin (3), apiosylskimmin (4), and magnolioside (5), were isolated and evaluated for in vitro antiplasmodial activity, as well as for their cytotoxic potential on SK-OV-3 cancer cell lines. Compounds 1 and 5 showed notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum with IC(50) values of 5.3 and 8.2 μM. The compounds showed no significant cytotoxicity (IC(50) > 100 μM) toward the SK-OV-3 cancer cell line.
    CONCLUSIONS:
    This is the first report on the antiplasmodial activity of these coumarin derivatives from the dried root of A. gigas.
    Phytochemistry Letters, 2016 , 18 :23-28.
    Chemical composition, antibacterial, antioxidant and tyrosinase inhibitory activities of glycosides from aerial parts of Eryngium tricuspidatum L.[Reference: WebLink]
    Two new phenolic glucosides, together with six known compounds, were isolated from the aerial part of Eryngium tricuspidatum L. (Apiaceae).
    METHODS AND RESULTS:
    The structures of the new compounds were established as 2-hydroxy- 3,5-dimethyl-acetophenon-4-O-β-d-glucopyranoside (1) and 2,3-dimethyl-4-hydroxymethylphenyl-1-hydroxymethyl-O-β-d-glucopyranoside (2) on the basis of detailed spectroscopic data including MS, 1D, and 2D NMR. The antibacterial, tyrosinase inhibitory and DPPH radical scavenging activities of hydromethanolic extract, fractions, and the eight isolated compounds were evaluated. The antibacterial assay showed a moderate activity for Magnolioside (4) against Staphylococcus aureus CIP 53.154. Compound 7 (quercetin 3-O-β-d-glucopyranosyl-(1 → 6)-O-β-d-galactopyranoside) had moderate DPPH radical scavenging activity whereas compounds 2 exhibited good inhibitory effect against mushroom tyrosinase.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.8225 mL 14.1123 mL 28.2247 mL 56.4493 mL 70.5617 mL
    5 mM 0.5645 mL 2.8225 mL 5.6449 mL 11.2899 mL 14.1123 mL
    10 mM 0.2822 mL 1.4112 mL 2.8225 mL 5.6449 mL 7.0562 mL
    50 mM 0.0564 mL 0.2822 mL 0.5645 mL 1.129 mL 1.4112 mL
    100 mM 0.0282 mL 0.1411 mL 0.2822 mL 0.5645 mL 0.7056 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    秦皮甲素; Esculin CFN99114 531-75-9 C15H16O9 = 340.28 20mg QQ客服:1413575084
    异莨菪亭; Isoscopoletin CFN97684 776-86-3 C10H8O4 = 192.17 20mg QQ客服:215959384
    6-甲氧基香豆素-7-0-beta-D-吡喃葡萄糖苷; Magnolioside CFN90699 20186-29-2 C16H18O9 = 354.3 10mg QQ客服:1413575084
    东莨菪内酯; 莨菪亭; Scopoletin CFN97494 92-61-5 C10H8O4 = 192.2 20mg QQ客服:1413575084
    乙酸东莨菪素酯; Scopoletin acetate CFN98951 56795-51-8 C12H10O5 = 234.2 5mg QQ客服:1413575084
    6-甲氧基-7-异戊烯氧基香豆素; 7-O-Prenylscopoletin CFN92639 13544-37-1 C15H16O4 = 260.3 5mg QQ客服:2056216494
    7-香叶草氧基-6-甲氧基香豆素; 7-Geranyloxy-6-methoxycoumarin CFN98348 28587-43-1 C20H24O4 = 328.4 10mg QQ客服:1413575084
    菊苣苷; Cichoriin CFN95196 531-58-8 C15H16O9 = 340.3 20mg QQ客服:215959384
    早开堇菜苷; Prionanthoside CFN95206 161842-81-5 C17H18O10 = 382.3 5mg QQ客服:215959384
    东莨菪甙; 东莨菪苷; Scopolin CFN98887 531-44-2 C16H18O9 = 354.3 20mg QQ客服:2159513211

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