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  • 四乙酰山奈酚; 四乙酸堪非醇酯

    Kaempferol tetraacetate

    四乙酰山奈酚; 四乙酸堪非醇酯
    产品编号 CFN99686
    CAS编号 16274-11-6
    分子式 = 分子量 C23H18O10 = 454.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Cudrania tricuspidata
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    四乙酰山奈酚; 四乙酸堪非醇酯 CFN99686 16274-11-6 1mg QQ客服:215959384
    四乙酰山奈酚; 四乙酸堪非醇酯 CFN99686 16274-11-6 5mg QQ客服:215959384
    四乙酰山奈酚; 四乙酸堪非醇酯 CFN99686 16274-11-6 10mg QQ客服:215959384
    四乙酰山奈酚; 四乙酸堪非醇酯 CFN99686 16274-11-6 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • The Institute of Cancer Research (United Kingdom)
  • University of Mysore (India)
  • University of Melbourne (Australia)
  • Macau University of Science and Technology (China)
  • Kitasato University (Japan)
  • University of Liège (Belgium)
  • Semmelweis Unicersity (Hungary)
  • Universitas islam negeri Jakarta (Indonesia)
  • University of Stirling (United Kingdom)
  • Weizmann Institute of Science (Israel)
  • University of the Basque Country (Spain)
  • University of Virginia (USA)
  • University of Auckland (New Zealand)
  • Melbourne University (Australia)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Tumour Biol.2015, 36(9):7027-34
  • Mediators Inflamm. 2016, 2016:6189590
  • Chemistr of plant2016, 2016021195
  • Molecules.2016, 21(6)
  • Korean Herb. Med. Inf. 2016, 4(1):35-42
  • Int J Oncol.2016, 49(4):1497-504
  • J of L. Chroma.&Related Tech2017, 252-258
  • J of Engineering Science&Technology2018, 13(9):2820-2828
  • Asian Journal of Chemistry2018, 30(12):2699-2703
  • Mol Cells.2018, 41(8):771-780
  • BMB Rep.2018, 51(5):249-254
  • J Sci Food Agric.2018, 98(3):1153-1161
  • J of Health Science and Alternative Medicine2019, 1(1)
  • Nutrients.2019, 11(4):E936
  • Biomed Pharmacother.2019, 116:108987
  • BMC Complement Altern Med.2019, 19(1):325
  • Biochem Biophys Res Commun.2019, 518(4):732-738
  • Cell Physiol Biochem.2019, 52(6):1255-1266
  • J Funct Foods2019, 54:449-456
  • Cell Mol Biol(Noisy-le-grand)2019, 65(7):77-83
  • Process Biochemistry2019, 87:213-220
  • Sci Rep.2019, 9:12132
  • Psychopharmacology (Berl).2020, 10.1007
  • ...
  • 生物活性
    Description: Kaempferol tetraacetate is a potent antiplatelet agent. It exhibits significant cytotoxicity in vitro against three human cell lines HL-60, U937 and SK-MEL-1.
    Targets: Antifection
    In vitro:
    J Nat Prod. 1993 Jun;56(6):929-34.
    Antiplatelet effects and vasorelaxing action of some constituents of Formosan plants.[Pubmed: 8350094]

    METHODS AND RESULTS:
    Various xanthones as well as quercetin have been shown to exhibit antiplatelet activity. A series of anthraquinones analogues structurally related to xanthones and a series of quercetin-related compounds were tested for their antiplatelet effects.
    CONCLUSIONS:
    Emodin, frangulin B, Kaempferol tetraacetate, quercetin-3-O-galactoside octaacetate, rhamnazin triacetate, and rhamnetin tetraacetate were found to be potent antiplatelet agents, and 1,8-dihydroxy-6-methoxy-3-methylanthraquinone 8-O-rhamnosyl-(1-->2)-glucoside, rhamnustrioside undecaacetate, rutin decaacetate, and quercetin-3-O-(6-O-alpha-L-arabinopyranosyl)-beta-D-galactopyranos ide decaacetate showed significant antiplatelet effects. Quercetin showed vasorelaxing action in rat thoracic aorta.
    Planta Med. 2008 Feb;74(2):171-4.
    Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana.[Pubmed: 18214815]

    METHODS AND RESULTS:
    The flavonoids kaempferol, quercetin, trifolin, hyperoside 2''- and 6''- acetates, 7-glucotrifolin, biorobin and robinin were isolated from the aerial parts of Consolida oliveriana.
    CONCLUSIONS:
    Their derivatives Kaempferol tetraacetate, quercetin pentaacetate, trifolin heptaacetate and hyperoside octaacetate exhibited significant cytotoxicity IN VITRO against three human cell lines HL-60, U937 and SK-MEL-1 while hyperoside 2''-acetate, hyperoside-6''-acetate, glucotrifolin decaacetate and heptamethyltrifolin were inactive.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2007 mL 11.0035 mL 22.007 mL 44.0141 mL 55.0176 mL
    5 mM 0.4401 mL 2.2007 mL 4.4014 mL 8.8028 mL 11.0035 mL
    10 mM 0.2201 mL 1.1004 mL 2.2007 mL 4.4014 mL 5.5018 mL
    50 mM 0.044 mL 0.2201 mL 0.4401 mL 0.8803 mL 1.1004 mL
    100 mM 0.022 mL 0.11 mL 0.2201 mL 0.4401 mL 0.5502 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    莰非醇-3,7,4'-三甲醚; Kaempferol 3,7,4'-trimethylether CFN96191 15486-34-7 C18H16O6 = 328.3 10mg QQ客服:1413575084
    山奈酚-5,7,4'-三甲醚; Kaempferol 5,7,4'-trimethyl ether CFN96292 1098-92-6 C18H16O6 = 328.3 5mg QQ客服:1148253675
    四甲基山奈酚; Tetramethylkaempferol CFN91889 16692-52-7 C19H18O6 = 342.34 5mg QQ客服:1413575084
    6-羟基山奈酚; 6-Hydroxykaempferol CFN92370 4324-55-4 C15H10O7 = 302.2 5mg QQ客服:2932563308
    Eupalitin; Eupalitin CFN70334 29536-41-2 C17H14O7 = 330.3 5mg QQ客服:2932563308
    3,6-二甲氧基芹菜素; 3,6-Dimethoxyapigenin CFN97961 22697-65-0 C17H14O7 = 330.3 5mg QQ客服:3257982914
    4',5-二羟基- 3,6,7-三甲氧基黄酮; Penduletin CFN98957 569-80-2 C18H16O7 = 344.3 5mg QQ客服:215959384
    草质素; Herbacetin CFN99778 527-95-7 C15H10O7 = 302.24 20mg QQ客服:1148253675
    8-甲氧基山奈酚; 8-甲氧基莰非醇; 8-Methoxykaempferol CFN92382 571-74-4 C16H12O7 = 316.3 5mg QQ客服:1413575084
    3,5,7-三羟基-8,4'-二甲氧基黄酮; Prudomestin CFN98453 3443-28-5 C17H14O7 = 330.3 5mg QQ客服:2159513211

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