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  • 3,9-二甲氧基紫檀碱; 高紫檀素

    Homopterocarpin

    3,9-二甲氧基紫檀碱; 高紫檀素
    产品编号 CFN97720
    CAS编号 606-91-7
    分子式 = 分子量 C17H16O4 = 284.31
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Flavonoids
    植物来源 The roots of Sophora tonkinensis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    3,9-二甲氧基紫檀碱; 高紫檀素 CFN97720 606-91-7 1mg QQ客服:3257982914
    3,9-二甲氧基紫檀碱; 高紫檀素 CFN97720 606-91-7 5mg QQ客服:3257982914
    3,9-二甲氧基紫檀碱; 高紫檀素 CFN97720 606-91-7 10mg QQ客服:3257982914
    3,9-二甲氧基紫檀碱; 高紫檀素 CFN97720 606-91-7 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Helmholtz Zentrum München (Germany)
  • Technical University of Denmark (Denmark)
  • Kyoto University (Japan)
  • Universiti Sains Malaysia (Malaysia)
  • Universidade do Porto (Portugal)
  • Universidade Federal de Goias (UFG) (Brazil)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • Universidade Federal de Santa Catarina (Brazil)
  • Indian Institute of Science (India)
  • Georgia Institute of Technology (USA)
  • Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)
  • Complutense University of Madrid (Spain)
  • VIT University (India)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Molecules. 2013, 18(7):7376-88
  • Front Pharmacol.2022, 13:806869.
  • Applied Biological Chemistry2022, 65(77).
  • Elife.2021, 10:e68058.
  • Environ Toxicol Pharmacol.2019, 66:109-115
  • Food Research2022, 6(6): 30-38.
  • BMC Complement Med Ther.2023, 23(1):264.
  • Int J Mol Sci.2021, 22(8):4211.
  • Separations2023, 10(11), 567;
  • LWT2021, 138:110630.
  • Auburn University2015, 1-58
  • Mol Pharm.2017, 14(9):3164-3177
  • J Asian Nat Prod Res.2019, 5:1-17
  • Ind Crops Prod.2014, 62:173-178
  • Chem Biol Interact.2018, 290:44-51
  • Pharmacogn Mag.2015, 11(43):562-6
  • J Nat Prod.2023, 86(2):264-275.
  • Analytical Letters.2020, doi 10.1008
  • Front Immunol.2018, 9:2091
  • Phytochem Anal.2023, pca.3305.
  • Plants (Basel).2021, 10(11):2317.
  • Journal of Food Quality2022, P:13, 6256310.
  • Korean Herb. Med. Inf.2021, 9(2):231-239.
  • ...
  • 生物活性
    Description: Homopterocarpin and Pterocarpus extract offer gastroprotection against indomethacin- induced ulcer by antioxidative mechanism and the modulation of gastric homeostasis, homopterocarpin may be responsible for, or contribute to the antiulcerogenic property of P. erinaceus. Homopterocarpin can contribute to the hepatoprotective and antioxidant potentials of P. erinaceus extract in acetaminophen-provoked hepatotoxicity. It can inhibit (lower concentration) or kill (higher concntration) human^s liver cancer cells under the cultured condition, they have anticancer activity. (-)-Homopterocarpin has active insect antifeedant against both S. litura and R. speratus. (+)-Homopterocarpin also has antimitotic effect.
    Targets: Antifection
    In vitro:
    Journal of Shenyang Pharmaceutical University,2001, 18(3):211-212.
    The inhibitory effects of homopterocarpin and medicarpin on human^s liver cancer cells in vitro[Reference: WebLink]
    An observation on the anticancer activity of Homopterocarpin and medicarpin in vitro, which was separated from the root of Glycyrrhiza pallidiflora Maxim.
    METHODS AND RESULTS:
    The cell culture test was used in these studies in vitro. The experimental result showed that these two ingredients could inhibite (lower concentration) or kill (higher concntration) human^s liver cancer cells under the cultured condition, moreover, the effect of medicarpin was stronger than that of Homopterocarpin.
    CONCLUSIONS:
    These two monomers were active components of Glycyrrhiza pallidiflora Maxim.
    In vivo:
    J Basic Clin Physiol Pharmacol. 2015 Mar 26.
    Effect of homopterocarpin, an isoflavonoid from Pterocarpus erinaceus, on indices of liver injury and oxidative stress in acetaminophen-provoked hepatotoxicity.[Pubmed: 25811665]
    Novel hepatoprotectives are needed to address the increasing cases of liver problems worldwide. Pterocarpus erinaceus Poir (Fabaceae) ethanol stem bark extract (PE) and its constituent flavonoid, homopterocarpin (HP), were investigated for their protective property in acetaminophen-induced oxidative stress and liver damage.
    METHODS AND RESULTS:
    Adult male albino rats were divided into nine groups. Seven groups were pretreated with PE (50-, 100-, and 150 mg/kg), HP (25-, 50-, and 75 mg/kg) or silymarin (25 mg/kg), respectively, once daily for 5 consecutive days and then administered acetaminophen (2 g/kg) on the 5th day. The control and acetaminophen-intoxicated groups received normal saline throughout the experimental period, with the latter group additionally receiving 2 g/kg acetaminophen on the 5th day. Administrations were performed po. In the acetaminophen-intoxicated group, there were significant increases (p<0.05) in serum activities of alanine aminotransferase (31.72±3.3 vs. 22.1±1.2 U/I), aspartate aminotransferase (185.1±10.1 vs. 103.83±13.3 U/I), bilirubin level and hepatic malondialdehyde (2.32±0.3 vs. 1.42±0.1 units/mg protein), accompanied with significant decreases (p<0.05) in hepatic reduced glutathione level (0.10±0.01 vs. 0.23±0.03 units/mg protein) and glutathione peroxidase activity (2.51±0.2 vs. 3.25±0.2 μmol H2O2 consumed/min/mg protein) compared with the control.
    CONCLUSIONS:
    PE and HP ameliorated most of the observed biochemical alterations with HP appearing to show more potency. The results suggest that the flavonoid, homopterocarpin contributes to the hepatoprotective and antioxidant potentials of P. erinaceus extract.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.5173 mL 17.5864 mL 35.1729 mL 70.3457 mL 87.9322 mL
    5 mM 0.7035 mL 3.5173 mL 7.0346 mL 14.0691 mL 17.5864 mL
    10 mM 0.3517 mL 1.7586 mL 3.5173 mL 7.0346 mL 8.7932 mL
    50 mM 0.0703 mL 0.3517 mL 0.7035 mL 1.4069 mL 1.7586 mL
    100 mM 0.0352 mL 0.1759 mL 0.3517 mL 0.7035 mL 0.8793 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Pterocarpadiol C; Pterocarpadiol C CFN89483 2055882-22-7 C16H14O7 = 318.27 5mg QQ客服:3257982914
    Pterocarpadiol B; Pterocarpadiol B CFN89481 2055882-20-5 C16H14O6 = 302.27 5mg QQ客服:1413575084
    Pterocarpadiol A; Pterocarpadiol A CFN89482 2055882-21-6 C16H12O7 = 316.26 5mg QQ客服:3257982914
    巴西苏木素; 苏枋精; Brazilin CFN98711 474-07-7 C16H14O5 = 286.3 20mg QQ客服:2056216494
    苏木精; Hematoxylin CFN96490 517-28-2 C16H14O6 = 302.28 20mg QQ客服:1457312923
    3,9-二羟基紫檀碱; 3,9-Dihydroxypterocarpan CFN97043 61135-91-9 C15H12O4 = 256.3 5mg QQ客服:215959384
    异美迪紫檀素; Isomedicarpin CFN97226 74560-05-7 C16H14O4 = 270.3 5mg QQ客服:1413575084
    美迪紫檀素; Medicarpin CFN98411 32383-76-9 C16H14O4 = 270.3 10mg QQ客服:215959384
    美迪紫檀素-3-O-葡萄糖苷; Medicarpin 3-O-glucoside CFN89498 52766-70-8 C22H24O9 = 432.42 5mg QQ客服:1413575084
    Glycinol; Glycinol CFN95122 69393-95-9 C15H12O5 = 272.3 5mg QQ客服:3257982914

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