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  • 高车前素 7-O-新橙皮糖苷

    Hispidulin 7-O-neohesperidoside

    高车前素 7-O-新橙皮糖苷
    产品编号 CFN90892
    CAS编号 156186-00-4
    分子式 = 分子量 C28H32O15 = 608.6
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Flavonoids
    植物来源 The herbs of Plantago asiatica L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    高车前素 7-O-新橙皮糖苷 CFN90892 156186-00-4 1mg QQ客服:215959384
    高车前素 7-O-新橙皮糖苷 CFN90892 156186-00-4 5mg QQ客服:215959384
    高车前素 7-O-新橙皮糖苷 CFN90892 156186-00-4 10mg QQ客服:215959384
    高车前素 7-O-新橙皮糖苷 CFN90892 156186-00-4 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Queensland (Australia)
  • Weizmann Institute of Science (Israel)
  • Northeast Normal University Changchun (China)
  • Johannes Gutenberg University Mainz (JGU) (Germany)
  • Chinese University of Hong Kong (China)
  • Korea Intitute of Science and Technology (KIST) (Korea)
  • Melbourne University (Australia)
  • Complutense University of Madrid (Spain)
  • Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)
  • Uniwersytet Jagielloński w Krakowie (Poland)
  • University of Madras (India)
  • Aarhus University (Denmark)
  • Institute of Bioorganic Chemistry Polish Academy of Sciences (Poland)
  • Funda??o Universitária de Desenvolvimento (Brazil)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Cell.2022, 185(23):4298-4316.e21.
  • Int J Mol Sci.2022, 23(21):12816.
  • Evid Based Complement Alternat Med.2020, 2020:9416962.
  • Korean J. Medicinal Crop Sci.2022, 30(2):117-123.
  • J Chromatogr B Analyt Technol Biomed Life Sci. 2017, 1064:115-123
  • Molecules.2016, 21(6)
  • Tissue Cell.2022, 78:101901.
  • Pamukkale Medical Journal2022, 15(4):796-803.
  • Sci Rep.2019, 9:19059
  • Exp Parasitol.2017, 183:160-166
  • Cancers (Basel).2021, 13(17):4327.
  • Clin Transl Med.2021, 11(5):e392.
  • Front Pharmacol.2019, 10:1025
  • Mol Med Rep.2022, 25(1):8.
  • Cell Death Differ.2021, 1-8.
  • Sci Rep.2020, 10:4495(2020)
  • Plant Growth Regulation2020, 90(2):383-392
  • Industrial Crops and Products2018, 353-362
  • Toxicol Rep.2021, 8:1131-1142.
  • Biomed Pharmacother.2022, 145:112410.
  • J Cell Mol Med.2023, jcmm.18071.
  • LWT2021, 138:110630.
  • J Chromatogr A.2022, 1685:463640.
  • ...
  • 生物活性
    Description: Hispidulin 7-O-neohesperidoside is one of the active substances responsible for the protective effects of this plant.
    In vivo:
    Phytother Res. 2004 Jan;18(1):19-24.
    Effects of methanol extract of Cirsium japonicum var. ussuriense and its principle, hispidulin-7-O-neohesperidoside on hepatic alcohol-metabolizing enzymes and lipid peroxidation in ethanol-treated rats.[Pubmed: 14750195]
    Effects of the methanol extract of Cirsium japonicum var. ussuriense and Hispidulin 7-O-neohesperidoside isolated from the plant on hepatic alcohol-metabolizing enzymes and lipid peroxidation were studied in rats treated with ethanol.
    METHODS AND RESULTS:
    Rats treated with 10% alcohol solution for 6 weeks were orally administered with 250 or 500 mg of methanol extract or 10 or 20 mg of Hispidulin 7-O-neohesperidoside per kg body weight daily during the last week of ethanol treatment. The administration of the methanol extract of herbal plant and Hispidulin 7-O-neohesperidoside in ethanol-treated rats significantly enhanced the activities of hepatic alcohol dehydrogenase, microsomal ethanol-oxidizing system and aldehyde dehydrogenase in a dose-dependent manner. The extract and the compound decreased hepatic lipid peroxidation along with an increase in hepatic content of reduced glutathione. The methanol extract and Hispidulin 7-O-neohesperidoside of C. japonicum var. ussuriense also increased the activity of glutathione reductase, but had no effect on gamma-glutamylcysteine synthase.
    CONCLUSIONS:
    The results suggest that C. japonicum var. ussuriense may alleviate alcoholic toxicity by enhancing ethanol oxidation as well as inhibiting lipid peroxidation, and Hispidulin 7-O-neohesperidoside is one of the active substances responsible for the protective effects of this plant.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6431 mL 8.2156 mL 16.4312 mL 32.8623 mL 41.0779 mL
    5 mM 0.3286 mL 1.6431 mL 3.2862 mL 6.5725 mL 8.2156 mL
    10 mM 0.1643 mL 0.8216 mL 1.6431 mL 3.2862 mL 4.1078 mL
    50 mM 0.0329 mL 0.1643 mL 0.3286 mL 0.6572 mL 0.8216 mL
    100 mM 0.0164 mL 0.0822 mL 0.1643 mL 0.3286 mL 0.4108 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    芹甙元-7-葡萄糖苷; Cosmosiin CFN98981 578-74-5 C21H20O10 = 432.4 20mg QQ客服:1413575084
    芹菜素7-O-(6”-O-丙二酸单酰)-β-D-葡萄糖苷; Apigenin 7-O-(6''-O-malonylglucoside) CFN95163 86546-87-4 C24H22O13 = 518.4 5mg QQ客服:3257982914
    Chamaemeloside; Chamaemeloside CFN70289 173356-77-9 C27H28O14 = 576.5 5mg QQ客服:215959384
    芹菜素-7-O-葡萄糖醛酸苷; Apigenin-7-glucuronide CFN98500 29741-09-1 C21H18O11 = 446.36 20mg QQ客服:2056216494
    芹菜素-7-O-葡萄糖醛酸甲酯苷; Apigenin 7-O-methylglucuronide CFN98894 53538-13-9 C22H20O11 = 460.4 5mg QQ客服:3257982914
    芹菜素 7,4'-二葡萄糖苷; Apigenin 7,4'-diglucoside CFN95648 31737-50-5 C27H30O15 = 594.5 5mg QQ客服:215959384
    5-O-beta-D-吡喃葡萄糖苷芹菜甙元; Apigenin 5-O-beta-D-glucopyranoside CFN98352 28757-27-9 C21H20O10 = 432.4 10mg QQ客服:2159513211
    芹菜苷; Apiin CFN90165 26544-34-3 C26H28O14 = 564.49 20mg QQ客服:3257982914
    芹菜素 7-[鼠李糖-(1->2)-半乳糖醛酸苷]; Apigenin 7-[rhamnosyl-(1->2)-galacturonide] CFN95352 124167-97-1 C27H28O15 = 592.5 10mg QQ客服:215959384
    芹菜素 7-二葡萄糖苷酸; Apigenin 7-diglucuronide CFN91599 74696-01-8 C27H26O17 = 622.5 5mg QQ客服:1413575084

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