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  • 灯盏花苷C

    Erigeside C

    灯盏花苷C
    产品编号 CFN99227
    CAS编号 112667-09-1
    分子式 = 分子量 C15H20O10 = 360.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The herbs of Erigeron breviscapus
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    灯盏花苷C CFN99227 112667-09-1 1mg QQ客服:1457312923
    灯盏花苷C CFN99227 112667-09-1 5mg QQ客服:1457312923
    灯盏花苷C CFN99227 112667-09-1 10mg QQ客服:1457312923
    灯盏花苷C CFN99227 112667-09-1 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Osmania University (India)
  • Massachusetts General Hospital (USA)
  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • Funda??o Universitária de Desenvolvimento (Brazil)
  • Florida A&M University (USA)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Med Food.2019, 22(10):1067-1077
  • Pharmaceutical Chemistry Journal2019, 52(12):986-991
  • Cells.2021, 10(10):2633.
  • Evid Based Complement Alternat Med.2018, 2018:4259603
  • Natural Product Communications2020, doi: 10.1177.
  • Recent Pat Anticancer Drug Discov.2022, 17(4):416-426.
  • Molecules.2022, 27(7):2116.
  • Anticancer Res.2018, 38(4):2127-2135
  • Molecules 2021, 26(4),1092.
  • Eur J Pharmacol.2020, 889:173589.
  • Process Biochemistry2019, 87:213-220
  • Drug Dev Res.2020, doi: 10.1002
  • Eur J Pharmacol.2021, 906:174220.
  • Phytochem Anal.2021, 32(6):970-981.
  • J. of The Korean Society of Food Culture2017, 144-149
  • Environ Toxicol.2020, doi: 10.1002
  • Int Immunopharmacol.2023, 123:110572.
  • J Applied Biological Chemistry2021, 64(2):185-192
  • Res Rep Urol.2022, 14:313-326.
  • Chemistry of Natural Compounds2020, 56,423-426
  • Int Immunopharmacol. 2020, 83:106403.
  • Asian J Beauty Cosmetol2019, 17(3):287-294
  • Plants (Basel).2021, 10(2):278.
  • ...
  • 生物活性
    Description: Standard reference
    In vitro:
    Nat Prod Commun. 2013 Feb;8(2):181-2.
    Phenolic glycosides from Lindera obtusiloba and their anti-allergic inflammatory activities.[Pubmed: 23513723]
    Eight phenolic glycosides, tachioside (1), isotachioside (2), koaburaside (3), 2,6-dimethoxy-4-hydroxyphenyl-1-O-beta-D-glucopyranoside (4), 4,6-dihydroxy-2-methoxyphenyl-1-O-beta-D-glucopyranoside (5), a mixture of Erigeside C (6a) and salidroside (6b), and 6-hydroxyphenyl)-1-O-beta-D-glucopyranoside (7) were isolated from the stems of Lindera obtusiloba Blume. The structures of the isolates were determined by 1H-, 13C-NMR, COSY, HMQC, and HMBC spectroscopy.
    METHODS AND RESULTS:
    To evaluate their anti-allergic inflammatory activities, the inhibitory effects of isolates (1-7) on histamine release and on the gene expressions of tumor necrosis factor (TNF)-a and interleukin (IL)-6 were examined using human mast cells; previous studies have reported that TNF-alpha and IL-6 release from mast cells is positively related to the severity of allergic symptoms. Of the tested compounds, koaburaside (3), 2,6-dimethoxy-4-hydroxyphenyl-1-O-beta-D-glucopyranoside (4), and (6-hydroxyphenyl)-1-O-beta-D-glucopyranoside (7) suppressed histamine release from mast cells as compared with gallic acid (positive control). In particular, 6-hydroxyphenyl)-1-O-beta-D-glucopyranoside (7) attenuated the gene expressions of the proinflammatory cytokines TNF-alpha and IL-6 in human mast cells.
    CONCLUSIONS:
    Our results support the notion that phenolic glycosides isolated from L. obtusiloba inhibit mast-cell-derived allergic inflammation, histamine, and proinflammatory cytokines.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.7755 mL 13.8773 mL 27.7546 mL 55.5093 mL 69.3866 mL
    5 mM 0.5551 mL 2.7755 mL 5.5509 mL 11.1019 mL 13.8773 mL
    10 mM 0.2775 mL 1.3877 mL 2.7755 mL 5.5509 mL 6.9387 mL
    50 mM 0.0555 mL 0.2775 mL 0.5551 mL 1.1102 mL 1.3877 mL
    100 mM 0.0278 mL 0.1388 mL 0.2775 mL 0.5551 mL 0.6939 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    3,4,5-三甲氧基苯甲酸; Trimethylgallic acid CFN92508 118-41-2 C10H12O5 = 212.2 20mg QQ客服:1413575084
    3,4,5-三甲氧基苯甲酸甲酯; Trimethylgallic acid methyl ester CFN92412 1916-07-0 C11H14O5 = 226.2 20mg QQ客服:1413575084
    2,3-二羟基-4-甲氧基苯甲酸; 2,3-Dihydroxy-4-methoxybenzoic acid CFN94481 3934-81-4 C8H8O5 = 184.1 5mg QQ客服:1457312923
    2-羟基-3,4-二甲氧基苯甲酸; 2-Hydroxy-3,4-dimethoxybenzoic acid CFN94461 5653-46-3 C9H10O5 = 198.17 5mg QQ客服:2159513211
    3,4-二甲氧基-2-羟基苯甲酸甲酯; Methyl 2-hydroxy-3,4-dimethoxybenzoate CFN95383 6395-23-9 C10H12O5 = 212.2 5mg QQ客服:215959384
    没食子酸; 3,4,5-三羟基苯甲酸; Gallic acid CFN99624 149-91-7 C7H6O5 = 170.1 20mg QQ客服:3257982914
    没食子酸甲酯; Methyl gallate CFN93180 99-24-1 C8H8O5 = 184.15 20mg QQ客服:1457312923
    丁香酸; Syringic acid CFN98884 530-57-4 C9H10O5 = 198.2 20mg QQ客服:215959384
    丁香酸甲酯; Methyl syringate CFN97450 884-35-5 C10H12O5 = 212.2 20mg QQ客服:1457312923
    葡萄糖基丁香酸; Glucosyringic acid CFN98426 33228-65-8 C15H20O10 = 360.3 5mg QQ客服:1413575084

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