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  • Elgonica dimer A

    Elgonica dimer A

    Elgonica dimer A
    产品编号 CFN95445
    CAS编号 132210-48-1
    分子式 = 分子量 C36H30O14 = 686.6
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Anthraquinones
    植物来源
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Elgonica dimer A CFN95445 132210-48-1 1mg QQ客服:2056216494
    Elgonica dimer A CFN95445 132210-48-1 5mg QQ客服:2056216494
    Elgonica dimer A CFN95445 132210-48-1 10mg QQ客服:2056216494
    Elgonica dimer A CFN95445 132210-48-1 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Wageningen University (Netherlands)
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  • Melbourne University (Australia)
  • Medical University of Gdansk (Poland)
  • Helmholtz Zentrum München (Germany)
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  • University of Canterbury (New Zealand)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Agric Food Chem.2021, 69(14):4210-4222.
  • International J of Green Pharmacy2019, 13(3)
  • Sci Rep.2017, 7:467-479
  • Pharmacognosy Magazine2017, 13(52):868-874
  • Int J Mol Sci.2019, 20(14):E3538
  • The Catharanthus Genome2022,35-83.
  • Int J Mol Sci.2021, 22(11):5503.
  • Anesth Pain Med (Seoul).2020, 15(4):478-485.
  • Biomed Pharmacother.2021, 139:111585.
  • Cancer Sci.2022, 113(4):1406-1416.
  • Nutrients2020, 12(2):488
  • Korean Herb. Med. Inf.2020, 8(2):233-242.
  • Eur J Pharmacol.2020, 889:173589.
  • Biol Pharm Bull.2018, 41(1):65-72
  • Phytother Res.2018, 32(5):923-932
  • Nutrients.2018, 10(12):E1998
  • Pharmaceuticals (Basel).2020, 13(9):262.
  • Molecules.2020, 25(21):5091.
  • Plos One.2019, 15(2):e0220084
  • Drug Dev Res.2022, 83(7):1673-1682.
  • Oncol Rep.2019, 41(4):2453-2463
  • Phytother Res.2015, 29(7):1088-96
  • Foods.2022, 11(12):1708.
  • ...
  • 生物活性
    In vitro:
    Yao Xue Xue Bao . 2006 Oct;41(10):1000-1003.
    [Active constituents from Aloe arborescens as BACE inhibitors][Pubmed: 17184120]
    Aim: To seek for new components as BACE inhibitors from Aloe arborescens. Methods: The chemical constituents were isolated by chromatographic methods and their structures were elucidated on the basis of spectral analysis. Results: Eight compounds were isolated and their structures identified as 6'-O-isobutyryl aloenin A (1), aloenin A (2), aloe-emodin (3), (E)-2-acetonyl-8-(2'-O-feruloxyl)-beta-D-glucopyranosyl-7-methoxy-5-methyl-chromone (4), 7-O-methylaloeresin A (5), babarloin A (6), elgonica-dimer A (7), and elgonica-dimer B (8), separately. Conclusion: Compound 1 is a new compound, and compound 4 was isolated from A. arborescens for the first time. Pharmacological tests indicated that 2, 4, 5 and 6 have moderate inhibitory active on BACE.
    In vivo:
    Planta Med . 2001 Nov;67(8):757-760.
    Hypotensive effect of chemical constituents from Aloe barbadensis[Pubmed: 11731923]
    Hypotensive effects of aloeemodin, aloin A, elgonica dimer A and bisbenzopyran from Aloe barbadensis have been studied. Aloeemodin has emerged as a potent hypotensive agent in current pharmacological investigations and caused 26 %, 52 %, and 79 % falls in mean arterial blood pressure at the corresponding doses of 0.5, 1, and 3 mg/kg in rats. The paper also describes the absolute configuration of elgonica dimer A (1).
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.4565 mL 7.2823 mL 14.5645 mL 29.129 mL 36.4113 mL
    5 mM 0.2913 mL 1.4565 mL 2.9129 mL 5.8258 mL 7.2823 mL
    10 mM 0.1456 mL 0.7282 mL 1.4565 mL 2.9129 mL 3.6411 mL
    50 mM 0.0291 mL 0.1456 mL 0.2913 mL 0.5826 mL 0.7282 mL
    100 mM 0.0146 mL 0.0728 mL 0.1456 mL 0.2913 mL 0.3641 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    9-O-Ethyldeacetylorientalide; 9-O-Ethyldeacetylorientalide CFN89009 1258517-60-0 C21H26O7 = 390.43 5mg QQ客服:215959384
    三尖杉碱; Cephalotaxine CFN90919 24316-19-6 C18H21NO4 = 315.4 20mg QQ客服:1413575084
    4'-O-甲氧基葛根素; 4'-Methoxypuerarin CFN90782 92117-94-7 C22H22O9 = 430.4 10mg QQ客服:3257982914
    Zosuquidar (LY335979) 3HCl; Zosuquidar (LY335979) 3HCl CFN60302 167465-36-3 C32H31F2N3O2.3HCl = 636.99 5mg QQ客服:215959384

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