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  • 狗牙花碱E

    Coronarin E

    狗牙花碱E
    产品编号 CFN99275
    CAS编号 117591-81-8
    分子式 = 分子量 C20H28O = 284.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Diterpenoids
    植物来源 The rhizomes of Hedychium coronarium
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    狗牙花碱E CFN99275 117591-81-8 1mg QQ客服:215959384
    狗牙花碱E CFN99275 117591-81-8 5mg QQ客服:215959384
    狗牙花碱E CFN99275 117591-81-8 10mg QQ客服:215959384
    狗牙花碱E CFN99275 117591-81-8 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Food Chemistry: X2023, 101032.
  • Int J Mol Sci.2022, 23(11):6172.
  • Food Chem.2016, 191:81-90
  • Int J Mol Sci.2022, 23(13):7115.
  • J of Applied Biological Chem.2020, 63(2):147-152
  • Life (Basel).2021, 11(7):616.
  • Int J Mol Sci.2021, 22(17):9400.
  • Molecules.2023, 28(13):4971.
  • World J Mens Health.2019, 10.5534
  • Phytomedicine.2021, 2(82):153452
  • AMB Express2020. 10(1):126.
  • Plos One.2019, 15(2):e0220084
  • Adaptive Medicine 2020, 12(1): 4-10
  • Phytother Res.2022, 10.1002:ptr.7602.
  • Phytomedicine.2017, 24:77-86
  • Am J Chin Med.2022, 1-20.
  • Plants (Basel).2021, 10(7):1376.
  • Int Immunopharmacol.2023, 125:111175.
  • Antioxidants (Basel).2021, 10(3):379.
  • Phytomedicine.2023, 117:154929.
  • Korean J. Medicinal Crop Sci.2022, 30(2):117-123.
  • Industrial Crops and Products2017, 95:286-295
  • Metabolites2023, 13(1), 3.
  • ...
  • 生物活性
    Description: Coronarin E exhibits weak antimicrobial activity.
    Targets: Antifection
    In vitro:
    Asian J. Pharm. Clin. Res., 2015, 8(5):221-6.
    Chemical composition and antimicrobial activity of diterpene and essential oils of hedychium roxburghii blume rhizome[Reference: WebLink]
    The objective of the present study was to isolate and determine diterpene compound and essential oils from Hedychium roxburghii Blume rhizome and investigated those antimicrobial activities.
    METHODS AND RESULTS:
    The essential oils were obtained by steam distillation method, the residual was then extracted by reflux with ethanol. The content of essential oils was analyzed by gas chromatography-mass spectrometry (GC/MS) method. Ethanolic residual-distillation extract was concentrated then used to isolate compound 1 by vacuum liquid chromatography and centrifugal chromatography. It was characterized by infrared spectrophotometry, 1H-nuclear magnetic resonance (NMR), 13C-NMR, heteronuclear single quantum coherence-NMR, heteronuclear multiple bond correlation-NMR and carbon coupling 13C-NMR. The antimicrobial activity of essential oils, ethanolic residual-distillation extract and compound 1 were carried out by microdilution method. The oils exhibited antimicrobial activity against Bacillus subtilis American Type Culture Collection (ATCC) 6633 (minimum inhibitory concentration [MIC] 1750 μg/ml), Staphylococcus aureus ATCC 6538 (MIC 1750 μg/ml), Escherichia coli ATCC 8939 (MIC 3500 μg/ml), Pseudomonas aeruginosa ATCC 9027 (>3500 μg/ml) and Candida albicans ATCC 10231 (MIC 875 μg/ml). A phytochemical study of the rhizome essential oils of H. roxburghii Blume were performed by GC/MS and the result showed that fenchyl acetate (45.85%) was the main component of the oils. Compound 1 was identified as diterpene compound, coronarin E. Coronarin E have not exhibited MIC at 512 μg/ml, however, it showed inhibition profile against all of tested microbes.
    CONCLUSIONS:
    The essential oils and ethanolic residual-distillation extract of H. roxburghii Blume rhizome exhibited weak antimicrobial profile. Compound 1 was identified as diterpene compound, (coronarin E), it was exhibited weak antimicrobial activity, but showed inhibition profile against all of the tested microbes.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.5162 mL 17.5809 mL 35.1617 mL 70.3235 mL 87.9044 mL
    5 mM 0.7032 mL 3.5162 mL 7.0323 mL 14.0647 mL 17.5809 mL
    10 mM 0.3516 mL 1.7581 mL 3.5162 mL 7.0323 mL 8.7904 mL
    50 mM 0.0703 mL 0.3516 mL 0.7032 mL 1.4065 mL 1.7581 mL
    100 mM 0.0352 mL 0.1758 mL 0.3516 mL 0.7032 mL 0.879 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    狗牙花碱E; Coronarin E CFN99275 117591-81-8 C20H28O = 284.4 5mg QQ客服:2159513211
    姜花素A; 狗牙花碱A; Coronarin A CFN99301 119188-33-9 C20H28O2 = 300.4 5mg QQ客服:2159513211
    滇姜花素A; Yunnancoronarin A CFN99689 162762-93-8 C20H28O2 = 300.4 5mg QQ客服:1413575084
    果药烯酮; Hedychenone CFN98942 56324-54-0 C20H26O2 = 298.4 5mg QQ客服:2056216494
    11,12-二氢-7-羟基草果药烯酮; 11,12-Dihydro-7-hydroxyhedychenone CFN89088 60149-07-7 C20H28O3 = 316.44 5mg QQ客服:2056216494
    Isoleojaponin; Isoleojaponin CFN89151 1840966-49-5 C20H26O3 = 314.42 5mg QQ客服:3257982914
    8-Acetoxy-15,16-epoxy-8,9-secolabda-13(16),14-diene-7,9-dione; 8-Acetoxy-15,16-epoxy-8,9-secolabda-13(16),14-diene-7,9-dione CFN89116 76475-32-6 C22H32O5 = 376.49 5mg QQ客服:215959384
    6-Dehydroxy-8-hydroxygaleopsinolone; 6-Dehydroxy-8-hydroxygaleopsinolone CFN89108 87440-66-2 C20H28O3 = 316.44 5mg QQ客服:2159513211
    Persianone; Persianone CFN89065 170894-20-9 C40H56O6 = 632.88 5mg QQ客服:2056216494
    Hispanone; Hispanone CFN89110 82462-67-7 C20H28O2 = 300.44 5mg QQ客服:1413575084

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