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  • 肉桂醇； beta-苯丙烯醇

    • 肉桂醇； beta-苯丙烯醇

    Cinnamyl alcohol

    肉桂醇； beta-苯丙烯醇
    		产品编号 CFN98119
    CAS编号 104-54-1
    分子式 = 分子量 C9H10O = 134.18
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenylpropanoids
    植物来源 The barks of Cinnamomum cassia Presl.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    肉桂醇； beta-苯丙烯醇 CFN98119 104-54-1 10mg QQ客服：2056216494
    肉桂醇； beta-苯丙烯醇 CFN98119 104-54-1 20mg QQ客服：2056216494
    肉桂醇； beta-苯丙烯醇 CFN98119 104-54-1 50mg QQ客服：2056216494
    肉桂醇； beta-苯丙烯醇 CFN98119 104-54-1 100mg QQ客服：2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Molecules.2019, 24(20):3755
  • Separations2021, 8(7),90.
  • Plants (Basel).2023, 12(22):3877.
  • Ecol Evol.2022, 12(11):e9459.
  • Phytomedicine.2016, 23(4):331-9
  • Int J Pharm.2022, 618:121636.
  • J Korean Soc Food Sci Nutr2023, 52(11):1101-1110
  • FEBS Lett.2015, 589(1):182-7
  • J Agric Food Chem.2018, 66(1):351-358
  • Front Plant Sci.2020, 10:1705
  • Microorganisms.2021, 9(12):2514.
  • Journal of Research in Pharmacy.2022, 26(6):p1752-1757.
  • J Ginseng Res.2020, 44(4):611-618.
  • Front Immunol.2020, 11:598556.
  • J Ethnopharmacol.2020, 254:112733.
  • Nat Commun.2021, 12(1):681.
  • Plant Pathology2022, 13527
  • Inflammation2015, 38(1):445-55
  • Nutrients.2020, 12(5):1242.
  • Pharmacognosy Magazine2018, 14(56):418-424
  • Front Chem.2022, 10:1048467.
  • Evid Based Complement Alternat Med.2021, 8855980.
  • Pharmaceuticals (Basel).2020, 13(9):262.
  • ...
    • 生物活性
    Description: Cinnamyl alcohol could as a fragrance ingredient with no safety concerns, it readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.
    In vitro:
    Contact Dermatitis. 2013 Mar;68(3):129-38.
    Cinnamyl alcohol oxidizes rapidly upon air exposure.[Pubmed: 23421457]
    Cinnamyl alcohol and cinnamal are frequent fragrance contact allergens. Both are included in the European baseline fragrance mix I, which is used for screening of contact allergy in dermatitis patients. The aim of this study was to investigate the autoxidation of Cinnamyl alcohol and to identify the oxidation products formed on air exposure. We also wanted to evaluate the effect of autoxidation on the sensitization potency of Cinnamyl alcohol.
    METHODS AND RESULTS:
    Samples of commercially available Cinnamyl alcohol with and without purification were exposed to air, and the autoxidation was followed by chemical analysis. The analysis was performed with mass spectrometry (LC/MS/MS). Sensitization potencies of compounds were determined with the murine local lymph node assay (LLNA) in mice. Chemical analysis showed that the concentration of Cinnamyl alcohol in the air-exposed samples decreased rapidly over time, and that autoxidation products were formed. Cinnamal, epoxy Cinnamyl alcohol and cinnamic acid were identified as oxidation products. According to our study, cinnamal and epoxy Cinnamyl alcohol were the first autoxidation products formed. The epoxy Cinnamyl alcohol was shown to be the oxidation product with the highest sensitization potency. The analysis of our samples of commercially available Cinnamyl alcohol showed that there was already a content of 1.5% cinnamal at the start of the autoxidation experiments.
    CONCLUSIONS:
    Cinnamyl alcohol readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the LLNA. Cinnamal was formed in the largest amounts, showing that cinnamal is not only formed via bioactivation, as has previously been shown. A highly sensitizing epoxide was also identified and quantified in the oxidation mixture.
    In vivo:
    Food Chem Toxicol. 2007;45 Suppl 1:S1-23.
    A toxicologic and dermatologic assessment of related esters and alcohols of cinnamic acid and cinnamyl alcohol when used as fragrance ingredients.[Pubmed: 18035463 ]
    A toxicologic and dermatologic assessment of related esters and alcohols of cinnamic acid and cinnamyl alcohol when used as fragrance ingredients.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 7.4527 mL 37.2634 mL 74.5268 mL 149.0535 mL 186.3169 mL
    5 mM 1.4905 mL 7.4527 mL 14.9054 mL 29.8107 mL 37.2634 mL
    10 mM 0.7453 mL 3.7263 mL 7.4527 mL 14.9054 mL 18.6317 mL
    50 mM 0.1491 mL 0.7453 mL 1.4905 mL 2.9811 mL 3.7263 mL
    100 mM 0.0745 mL 0.3726 mL 0.7453 mL 1.4905 mL 1.8632 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    反式-3,4,5-三甲氧基肉桂醇; 3,4,5-Trimethoxycinnamyl alcohol CFN98379 30273-62-2 C12H16O4 = 224.3 5mg QQ客服：1413575084
    3-苯基-2-丙烯-1-醇； 反式-肉桂醇; 3-Phenyl-2-propen-1-ol CFN98675 4407-36-7 C9H10O = 134.2 5mg QQ客服：1457312923
    乙酸肉桂酯； 乙酰肉桂醇; Cinnamyl acetate CFN98057 21040-45-9 C11H12O2 = 176.2 5mg QQ客服：2159513211
    3-(4-羟基苯基)-1-丙醇; 3-(4-Hydroxyphenyl)-1-propanol CFN99037 10210-17-0 C9H12O2 = 152.2 5mg QQ客服：2056216494
    对羟基肉桂醇; p-Coumaryl alcohol CFN96011 3690-05-9 C9H10O2 = 150.2 5mg QQ客服：2056216494
    4-Methoxycinnamyl alcohol; 4-Methoxycinnamyl alcohol CFN89230 53484-50-7 C10H12O2 = 164.20 5mg QQ客服：3257982914
    trans-3,4-Methylenedioxycinnamyl alcohol; trans-3,4-Methylenedioxycinnamyl alcohol CFN92410 58095-76-4 C10H10O3 = 178.2 5mg QQ客服：1457312923
    松柏醇; 反式-3-(4-羟基-3-甲氧基苯基)-2-丙烯-1-醇; Coniferyl alcohol CFN97760 32811-40-8 C10H12O3 = 180.20 20mg QQ客服：2056216494
    二氢松柏醇 ; Dihydroconiferyl alcohol CFN96742 2305-13-7 C10H14O3 = 182.21 5mg QQ客服：2056216494
    γ-甲氧基异丁子香酚; Gamma-Methoxyisoeugenol CFN96094 63644-71-3 C11H14O3 = 194.2 20mg QQ客服：3257982914

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