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  • 构树宁C

    Broussonin C

    构树宁C
    产品编号 CFN97690
    CAS编号 76045-49-3
    分子式 = 分子量 C20H24O3 = 312.41
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The branches of Broussonetia papyrifera
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    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    构树宁C CFN97690 76045-49-3 1mg QQ客服:1457312923
    构树宁C CFN97690 76045-49-3 5mg QQ客服:1457312923
    构树宁C CFN97690 76045-49-3 10mg QQ客服:1457312923
    构树宁C CFN97690 76045-49-3 20mg QQ客服:1457312923
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  • ...
  • 生物活性
    Description: Broussonin C and broussin are antifungal compounds. Broussonin C exerts simple reversible slow-binding inhibition against diphenolase.
    Targets: Tyrosinase | Antifection
    In vitro:
    Bioorg Med Chem. 2009 Jan 1;17(1):35-41.
    Tyrosinase inhibitory effects of 1,3-diphenylpropanes from Broussonetia kazinoki.[Pubmed: 19046886]

    METHODS AND RESULTS:
    Six 1,3-diphenylpropanes exhibiting inhibitory activities against both the monophenolase and diphenolase actions of tyrosinase were isolated from the methanol (95%) extract of Broussonetia kazinoki. These compounds, 1-6, were identified as kazinol C (1), D (2), F (3), Broussonin C (4), kazinol S (5) and kazinol T (6). The latter two species (5 and 6) emerged to be new 1,3-diphenylpropanes which we fully spectroscopically characterized. The IC(50) values of compounds (1, 3-5) for monophenolase inhibition were determined to range between 0.43 and 17.9 microM. Compounds 1 and 3-5 also inhibited diphenolase significantly with IC(50) values of 22.8, 1.7, 0.57, and 26.9 microM, respectively.
    CONCLUSIONS:
    All four active tyrosinase inhibitors (1, 3-5) were competitive inhibitors. Interestigly they all mainfested simple reversible slow-binding inhibition against diphenolase. The most potent inhibitor, Broussonin C diplayed the following kinetic parameters k(3)=0.0993 microM(-1)min(-1), k(4)=0.0048 min(-1), and K(i)(app)=0.0485 microM.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.2009 mL 16.0046 mL 32.0092 mL 64.0184 mL 80.023 mL
    5 mM 0.6402 mL 3.2009 mL 6.4018 mL 12.8037 mL 16.0046 mL
    10 mM 0.3201 mL 1.6005 mL 3.2009 mL 6.4018 mL 8.0023 mL
    50 mM 0.064 mL 0.3201 mL 0.6402 mL 1.2804 mL 1.6005 mL
    100 mM 0.032 mL 0.16 mL 0.3201 mL 0.6402 mL 0.8002 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    葛根苷C; Pueroside C CFN95156 112343-16-5 C24H26O10 = 474.5 5mg QQ客服:3257982914
    葛根苷B; Pueroside B CFN95141 100692-54-4 C30H36O15 = 636.6 10mg QQ客服:1413575084
    构树宁B; Broussonin B CFN97695 73731-86-9 C16H18O3 = 258.32 10 mg QQ客服:1457312923
    构树宁A; Broussonin A CFN97694 73731-87-0 C16H18O3 = 258.32 5mg QQ客服:1413575084
    构树宁C; Broussonin C CFN97690 76045-49-3 C20H24O3 = 312.41 5mg QQ客服:2056216494
    1-(4-羟基-2-甲氧基苯基)-3-(4-羟基-3-异戊烯基苯基)丙烷; 1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)propane CFN98607 376362-03-7 C21H26O3 = 326.4 5mg QQ客服:1413575084
    1-羟基-1-(4-羟基-2-甲氧基苯基)-3-(4-羟基苯基)-2-丙酮; 1-Hydroxy-1-(4-hydroxy-2-methoxyphenyl)-3-(4-hydroxyphenyl)propan-2-one CFN97846 117614-84-3 C16H16O5 = 288.3 5mg QQ客服:1457312923
    Puerol A; Puerol A CFN96269 152784-32-2 C17H14O5 = 298.3 5mg QQ客服:3257982914
    (+)-Puerol B 2''-O-glucoside; (+)-Puerol B 2''-O-glucoside CFN97602 868409-19-2 C24H26O10 = 474.46 10mg QQ客服:1457312923
    Puerol B; Puerol B CFN95155 112343-17-6 C18H16O5 = 312.3 5mg QQ客服:215959384

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