Info: Read More
  • 中药标准品生产商,产品定制服务
  • 香柑醇; 5-羟基-6,7-呋喃并香豆素

    Bergaptol

    香柑醇; 5-羟基-6,7-呋喃并香豆素
    产品编号 CFN98772
    CAS编号 486-60-2
    分子式 = 分子量 C11H6O4 = 202.2
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Coumarins
    植物来源 The roots of Notopterygium incisum.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    香柑醇; 5-羟基-6,7-呋喃并香豆素 CFN98772 486-60-2 10mg QQ客服:1413575084
    香柑醇; 5-羟基-6,7-呋喃并香豆素 CFN98772 486-60-2 20mg QQ客服:1413575084
    香柑醇; 5-羟基-6,7-呋喃并香豆素 CFN98772 486-60-2 50mg QQ客服:1413575084
    香柑醇; 5-羟基-6,7-呋喃并香豆素 CFN98772 486-60-2 100mg QQ客服:1413575084
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Illinois (USA)
  • University of Mysore (India)
  • University of Canterbury (New Zealand)
  • Sant Gadge Baba Amravati University (India)
  • The Ohio State University (USA)
  • Heidelberg University (Germany)
  • The Australian National University (Australia)
  • University of Queensland (Australia)
  • Chinese University of Hong Kong (China)
  • Helmholtz Zentrum München (Germany)
  • University of Lodz (Poland)
  • Wageningen University (Netherlands)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • Instituto de Investigaciones Agropecuarias (Chile)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Front Pharmacol.2021, 12:652860.
  • Food and Fermentation Industries2018, 44(371)
  • Int J Mol Sci.2022, 23(15):8687.
  • Evid Based Complement Alternat Med.2017, 2017:1583185
  • Phytochem Anal.2021, 32(6):970-981.
  • Kor. J. Herbol.2019, 34(2):59-66
  • Int J Mol Sci.2019, 20(16):E4015
  • Korean J Environ Agric.2018, 37(4):260-267
  • Antiviral Res.2021, 193:105142.
  • Revista Brasileira de Farmacognosia2021, 31:794-804.
  • Current Enzyme Inhibition2023, 19(1):55-64(10)
  • Journal of Ginseng Research2019, 10.1016
  • Phytother Res.2018, 32(5):923-932
  • Biol Pharm Bull.2018, 41(11):1645-1651
  • Life Sci.2019, 216:259-270
  • Plant Cell Tiss Org2017, 479-486
  • Antioxidants (Basel).2020, 9(4):284.
  • Chem Biol Interact.2019, 315:108910
  • Antioxidants (Basel).2021, 10(3):379.
  • PLoS One.2018, 13(3):e0193386
  • Food Chem.2021, 360:130063.
  • BMB Rep.2018, 51(5):249-254
  • Int. J. Mol. Sci.2022, 23(8), 4130.
  • ...
  • 生物活性
    Description: Bergaptol acts as a potent inhibitor of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 uM.Bergaptol shows very good radical scavenging activity, it induces dose-dependent cytotoxic effect on MCF-7 cell viability.
    Targets: CYP3A4
    In vitro:
    Bangl. J. Pharmacol., 2016, 11(2):489.
    Antitumor and apoptotic effects of bergaptol are mediated via mitochondrial death pathway and cell cycle arrest in human breast carcinoma cells.[Reference: WebLink]
    The aim of the present research work was to investigate the anti-cancer and apoptotic effects of Bergaptol in human breast cancer cells (MCF-7).
    METHODS AND RESULTS:
    The effects on cell cycle arrest and caspase activation were evaluated. MTT assay was used to evaluate the effect of the compound on cell viability. Cellular morphology was demonstrated by fluorescence microscopy. Flow cytometry was used to analyze effect of Bergaptol on cell cycle and apoptosis. The results revealed that Bergaptol induced dose-dependent cytotoxic effect on MCF-7 cell viability showing IC50 value of 52.2 μM. Bergaptol induced both early and late apoptosis in concentration-dependent manner. After treatment with Bergaptol, an increase in the proportion of cells in the S-phase (37.2, 45.3 and 65.1% as compared to 28.6% in untreated cells) and a reduction in the fraction of cells in the G1 phase (44.1, 41.6 and 35.2% as compared to 51.2% in the untreated cells) was observed.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.9456 mL 24.728 mL 49.456 mL 98.912 mL 123.64 mL
    5 mM 0.9891 mL 4.9456 mL 9.8912 mL 19.7824 mL 24.728 mL
    10 mM 0.4946 mL 2.4728 mL 4.9456 mL 9.8912 mL 12.364 mL
    50 mM 0.0989 mL 0.4946 mL 0.9891 mL 1.9782 mL 2.4728 mL
    100 mM 0.0495 mL 0.2473 mL 0.4946 mL 0.9891 mL 1.2364 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    异茴芹灵; Isopimpinellin CFN98752 482-27-9 C13H10O5 = 246.2 20mg QQ客服:2159513211
    Rivulobirin B; Rivulobirin B CFN99893 194145-29-4 C23H12O9 = 432.3 5mg QQ客服:1413575084
    三甲沙林; Trioxsalen CFN70355 3902-71-4 C14H12O3 = 228.2 5mg QQ客服:2056216494
    花椒毒酚,花椒毒醇; Xanthotoxol CFN98016 2009-24-7 C11H6O4 = 202.2 20mg QQ客服:2159513211
    花椒毒素; 8-甲氧基补骨脂素; Xanthotoxin CFN98372 298-81-7 C12H8O4 = 216.2 20mg QQ客服:215959384
    佛手酚葡萄糖苷; Bergaptol-beta-glucopyranoside CFN95186 131623-13-7 C17H16O9 = 364.3 10mg QQ客服:2056216494
    8-羟基-5-O-beta-D-吡喃葡萄糖补骨脂素; 8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen CFN98663 425680-98-4 C17H16O10 = 380.3 5mg QQ客服:1413575084
    香柑醇; 5-羟基-6,7-呋喃并香豆素; Bergaptol CFN98772 486-60-2 C11H6O4 = 202.2 20mg QQ客服:1413575084
    佛手苷内酯; Bergapten CFN98766 484-20-8 C12H8O4 = 216.2 20mg QQ客服:1413575084
    8-羟基佛手苷内酯; 8-Hydroxybergapten CFN90591 1603-47-0 C12H8O5 = 232.19 10mg QQ客服:2159513211

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 1413575084
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产