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  • Atalantoflavone

    Atalantoflavone

    Atalantoflavone
    产品编号 CFN97991
    CAS编号 119309-02-3
    分子式 = 分子量 C20H16O5 = 336.3
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Flavonoids
    植物来源 The fruits of Citrus medica
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Atalantoflavone CFN97991 119309-02-3 1mg QQ客服:1457312923
    Atalantoflavone CFN97991 119309-02-3 5mg QQ客服:1457312923
    Atalantoflavone CFN97991 119309-02-3 10mg QQ客服:1457312923
    Atalantoflavone CFN97991 119309-02-3 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Heidelberg University (Germany)
  • The Vancouver Prostate Centre (VPC) (Canada)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • University of Wollongong (Australia)
  • University of Padjajaran (Indonesia)
  • University of Bordeaux (France)
  • Florida A&M University (USA)
  • China Medical University (Taiwan)
  • Research Unit Molecular Epigenetics (MEG) (Germany)
  • Seoul National University (Korea)
  • Johannes Gutenberg University Mainz (JGU) (Germany)
  • University of Lodz (Poland)
  • Wageningen University (Netherlands)
  • Instituto de Investigaciones Agropecuarias (Chile)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • PLoS One.2018, 13(4):e0195642
  • Molecules.2020, 25(23):5636.
  • Sci Rep.2023, 13(1):14594.
  • Molecules.2018, 23(7):E1817
  • Life Sci.2023, 317:121458.
  • Antioxidants (Basel).2021, 10(3):379.
  • Chemistry of plant raw materials2021, 1:pp 139-150
  • ACS Pharmacol. Transl. Sci.2022, 5,7,479-490
  • Microb Pathog.2019, 131:128-134
  • J Ethnopharmacol.2017, 209:305-316
  • JAOCS2021, 98(7):779-794.
  • FEBS Lett.2015, 589(1):182-7
  • Molecules.2021, 26(23):7390.
  • Sci Rep.2017, 7:40345
  • Int J Cosmet Sci.2019, 41(1):12-20
  • Evid Based Complement Alternat Med.2022, 2022:3483511
  • Chem. of Vegetable Raw Materials2020, 97-105
  • Journal of Applied Pharmaceutical Science2022, 0(00), pp:001-007
  • BMC Complement Altern Med.2019, 19(1):367
  • Pharmacognosy Journal2019, 11,6:1235-1241
  • J Agric Food Chem.2021, 69(14):4210-4222.
  • Drug Des Devel Ther.2020, 14:61-71
  • European Journal of Integrative Medicine2018, 20:165-172
  • ...
  • 生物活性
    Description: Atalantoflavone shows urease inhibitory potential. It displays weak cytotoxic activity against the human Caucasian prostate adenocarcinoma cell line PC-3.
    Targets: Antifection
    In vitro:
    Bmc Complementary & Alternative Medicine, 2015 , 15 (1) :1-7.
    Antibacterial activities of the methanol extracts and compounds from Erythrina sigmoidea against Gram-negative multi-drug resistant phenotypes.[Pubmed: 26715029]

    METHODS AND RESULTS:
    In the present study, the methanol extracts from the leaves, as well as compounds namely sigmoidin I (1), Atalantoflavone (2), bidwillon A (3), neocyclomorusin (4), 6α-hydroxyphaseollidin (5) and neobavaisoflavone (6) (from the bark extract) were tested for their activities against a panel of Gram-negative bacteria including multi-drug resistant (MDR) phenotypes. Methods Broth microdilution method was used to determine the minimum inhibitory concentrations (MICs) and the minimum bactericidal concentrations (MBCs) of the extracts as well as compounds 1–6. Results The MIC results indicated that the crude extracts from the leaves and bark of this plant were able to inhibit the growth of 96.3 % of the 27 tested bacteria.
    CONCLUSIONS:
    Compounds 2–6 displayed selective activities, their inhibitory effects being obtained on 8.3 %, 41.7 %, 58.3 %, 58.3 % and 66.7 % of tested bacteria respectively for 2, 3, 5, 6 and 4. The lowest MIC value of 8 μg/mL was obtained with 6 against Escherichia coli ATCC8739, Enterobacter cloacae ECCI69, Klebsiella pneumoniae KP55, Providencia stuartii NAE16 and Pseudomonas aeruginosa PA01.
    Zeitschrift Für Naturforschung B, 2015 , 70 (1) :71-75.
    A prenylated acridone alkaloid and ferulate xanthone from barks of Citrus medica (Rutaceae)[Reference: WebLink]

    METHODS AND RESULTS:
    A new prenylated acridone alkaloid, medicacridone (1), and a new ferulate xanthone, medicaxanthone (5), together with 11 known compounds were isolated from the methanol extract of the bark of the Cameroonian medicinal plant Citrus medica. The structures of all compounds were determined by comprehensive analyses of their 1D and 2D NMR, mass spectral (EI and ESI) data, chemical reactions, and comparison with previously known analogues.
    CONCLUSIONS:
    The agar diffusion test delivered low to missing antimicrobial activities, corresponding with MICs > 1 mg mL–1, while compounds 1–6 and Atalantoflavone (9) displayed weak cytotoxic activity against the human Caucasian prostate adenocarcinoma cell line PC-3, with IC50 values ranging from 60.5 to 80.0 μm versus doxorubicine with IC50=0.9 μm.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.9735 mL 14.8677 mL 29.7354 mL 59.4707 mL 74.3384 mL
    5 mM 0.5947 mL 2.9735 mL 5.9471 mL 11.8941 mL 14.8677 mL
    10 mM 0.2974 mL 1.4868 mL 2.9735 mL 5.9471 mL 7.4338 mL
    50 mM 0.0595 mL 0.2974 mL 0.5947 mL 1.1894 mL 1.4868 mL
    100 mM 0.0297 mL 0.1487 mL 0.2974 mL 0.5947 mL 0.7434 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    朝藿素C; Epimedokoreanin C CFN91891 161068-54-8 C25H26O8 = 454.47 5mg QQ客服:2056216494
    5'-香叶基-5,7,2',4'-四羟基黄酮; 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone CFN92321 1221762-70-4 C25H26O6 = 422.5 5mg QQ客服:215959384
    Atalantoflavone; Atalantoflavone CFN97991 119309-02-3 C20H16O5 = 336.3 5mg QQ客服:1457312923
    6-异戊烯基芹菜苷元; 4',5,7-Trihydroxy-6-prenylflavone CFN97161 68097-13-2 C20H18O5 = 338.4 5mg QQ客服:2159513211
    5-羟基-8-(4-羟基苯基)-2,2-二甲基-2H,6H-苯并[1,2-B:5,4-B']二吡喃-6-酮; Carpachromene CFN98969 57498-96-1 C20H16O5 = 336.3 5mg QQ客服:1457312923
    桂木生黄素; Artocarpesin CFN91901 3162-09-2 C20H18O6 = 354.35 5mg QQ客服:1413575084
    Multicaulisin; Multicaulisin CFN90960 286461-76-5 C40H36O11 = 692.71 5mg QQ客服:2056216494
    Corylifol C; Corylifol C CFN92228 775351-91-2 C20H18O5 = 338.4 5mg QQ客服:1457312923
    8,3'-二异戊烯基芹菜素; 8,3'-Diprenylapigenin CFN96216 955135-37-2 C25H26O5 = 406.5 5mg QQ客服:2056216494
    Honyucitrin; Honyucitrin CFN97850 114542-44-8 C25H26O5 = 406.48 5mg QQ客服:1457312923

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