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  • Andropanolide

    Andropanolide

    Andropanolide
    产品编号 CFN97600
    CAS编号 869807-57-8
    分子式 = 分子量 C20H30O5 = 350.45
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Diterpenoids
    植物来源 The herbs of Andrographis paniculata (Burm. f.) Nees
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Andropanolide CFN97600 869807-57-8 1mg QQ客服:1413575084
    Andropanolide CFN97600 869807-57-8 5mg QQ客服:1413575084
    Andropanolide CFN97600 869807-57-8 10mg QQ客服:1413575084
    Andropanolide CFN97600 869807-57-8 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Amity University (India)
  • Instituto de Investigaciones Agropecuarias (Chile)
  • University of Zurich (Switzerland)
  • University of Liège (Belgium)
  • Kazusa DNA Research Institute (Japan)
  • Pennsylvania State University (USA)
  • Shanghai Institute of Organic Chemistry (China)
  • Chang Gung University (Taiwan)
  • University of Bordeaux (France)
  • Ain Shams University (Egypt)
  • Charles Sturt University (Denmark)
  • Universidade Católica Portuguesa (Portugal)
  • University of Helsinki (Finland)
  • University of Vigo (Spain)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Nat Prod Sci.2014, 20(3):182-190
  • Mol Med Rep.2014, 9(5):1653-9
  • BMC Complement Altern Med.2016, 16:213
  • Pharm Biol.2016, 54(7):1255-62
  • Jour. of Stored Pro & Postharvest Res.2016, 7(3):32-36
  • Oncotarget.2016, 8(51):88386-88400
  • Free Radic Biol Med.2017, 112:191-199
  • Int J Anal Chem.2017, 2017:1254721
  • Universite de Bordeaux2017, 2017BORD0867
  • Molecules.2017, 22(12)
  • Naunyn Schmiedebergs Arch Pharmacol.2017, 390(10):1073-1083
  • Front Pharmacol.2017, 8:205
  • Sci Rep. 2018, 10590
  • Phytochemistry2018, 15:83-92
  • International Food Research Journal2018, 25(6):2560-2571
  • Journal of Life Science2018, 917-922
  • J Cancer.2019, 10(23):5843-5851
  • Postharvest Biol Tec2019, 149:18-26
  • Int J Mol Sci.2019, 20(21):E5488
  • Molecules.2019, 24(9):E1719
  • J Clin Med.2019, 8(10):E1664
  • Biomed Chromatogr.2019, 8:e4774
  • Appl Biochem Biotechnol.2020, 190(2):732-744
  • ...
  • 生物活性
    Description: Andropanolide is a natural product from Andrographis paniculata (Burm. f.) Nees.
    In vitro:
    International Journal of Pharmacy & Pharmaceutical Sciences, 2014, 6(1):46–52.
    MICROBIAL METABOLISM OF AN ANTI-HIV AND ANTI-MALARIAL NATURAL PRODUCT ANDROGRAPHOLIDE[Reference: WebLink]
    In the present study, we first time studied the microbial metabolism of andrographolide (1) with Cunninghamella elegans (TSY 0865) and Cephalosporium aphidicola (IMI-68689).
    METHODS AND RESULTS:
    Microbial cultures of the C. elegans and C. aphidicola were grown on Potato dextrose agar (PDA) at 25°C and stored at 4°C. Medium for C. aphidicola was prepared by mixing Glucose (50.0 g), KH2PO4 (1.0 g), MgSO4.7H2O (2.0 g), Glycin (2.0 g), KCl (1.0 g) and Gibberella trace element solution (2.0 mL) into distilled water (1 L) and maintained pH at 5.6. While C. elegans medium was prepared by adding Glucose (10.0 g), peptone (5.0 g), KH2PO4 .Two compounds were obtained as transformed products. Based on physical and spectroscopic data, these have been identified as andropanolide (2) and 14-deoxy-11,12-didehydro andrographolide (3). Both compounds were previously obtained by the phytochemical investigation of A. paniculata and biotransformed product as well. (5.0 g), yeast extract (5.0 g), NaCl (5.0 g) and glycerol (10 mL) into distilled water (1 L) and maintained pH at 5.6.
    CONCLUSIONS:
    It could be concluded that C. elegans and C. aphidicola were able to produce oxidative derivatives of 1 in a regio- and stereoselective manner. Present investigation has been conducted for the first time with C. elegans and C. aphidicola. Incubation of 1 for 9 days with fungal strains yielded isomerized and oxidative products 2 and 3. Structures of all metabolites were elucidated by using spectroscopic techniques.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.8535 mL 14.2674 mL 28.5347 mL 57.0695 mL 71.3369 mL
    5 mM 0.5707 mL 2.8535 mL 5.7069 mL 11.4139 mL 14.2674 mL
    10 mM 0.2853 mL 1.4267 mL 2.8535 mL 5.7069 mL 7.1337 mL
    50 mM 0.0571 mL 0.2853 mL 0.5707 mL 1.1414 mL 1.4267 mL
    100 mM 0.0285 mL 0.1427 mL 0.2853 mL 0.5707 mL 0.7134 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Andropanolide; Andropanolide CFN97600 869807-57-8 C20H30O5 = 350.45 5mg QQ客服:215959384
    穿心莲内酯; Andrographolide CFN98923 5508-58-7 C20H30O5 = 350.5 20mg QQ客服:3257982914
    14-去氧-11,12-二去氢穿心莲内酯; 14-Deoxy-11,12-didehydroandrographolide CFN98666 42895-58-9 C20H28O4 = 332.4 20mg QQ客服:2932563308
    脱水穿心莲内酯; Dehydroandrographolide CFN99770 134418-28-3 C20H28O4 = 332.43 20mg QQ客服:3257982914
    14-去氧穿心莲内酯; 14-Deoxyandrographolide CFN92802 4176-97-0 C20H30O4 = 334.45 10mg QQ客服:215959384
    去氧穿心莲内酯; Deoxyandrographolide CFN90518 79233-15-1 C20H30O4 = 334.45 20mg QQ客服:1148253675
    14-去氧基-17-羟基穿心莲内酯; 14-Deoxy-17-hydroxyandrographolide CFN97601 869384-82-7 C20H32O5 = 352.47 5mg QQ客服:1148253675
    14-去氧基-11-羟基穿心莲内酯; 14-Deoxy-11-hydroxyandrographolide CFN97815 160242-09-1 C20H30O5 = 350.45 5mg QQ客服:2159513211
    14-去氧-12-羟基穿心莲内酯; 14-Deoxy-12-hydroxyandrographolide CFN97785 219721-33-2 C20H30O5 = 350.45 5mg QQ客服:1148253675
    Vitexolide D; Vitexolide D CFN96446 1788090-69-6 C20H30O3 = 318.45 5mg QQ客服:215959384

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