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  • 1-羟基-2-甲氧基蒽醌

    Alizarin 2-methyl ether

    1-羟基-2-甲氧基蒽醌
    产品编号 CFN92569
    CAS编号 6003-11-8
    分子式 = 分子量 C15H10O4 = 254.2
    产品纯度 >=98%
    物理属性 Red cryst.
    化合物类型 Anthraquinones
    植物来源 The roots of Rubia cordifolia
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    1-羟基-2-甲氧基蒽醌 CFN92569 6003-11-8 1mg QQ客服:1413575084
    1-羟基-2-甲氧基蒽醌 CFN92569 6003-11-8 5mg QQ客服:1413575084
    1-羟基-2-甲氧基蒽醌 CFN92569 6003-11-8 10mg QQ客服:1413575084
    1-羟基-2-甲氧基蒽醌 CFN92569 6003-11-8 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • Guangzhou Institutes of Biomedicine and Health (China)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Food Chem.2021, 377:131976.
  • Sci Rep. 2017, 12953(7)
  • Journal of Functional Foods2022, 91:105019.
  • Eur J Pharmacol.2022, 917:174744.
  • Biomed Pharmacother.2020, 125:109784.
  • Metabolites.2020, 10(11):440.
  • BMC Complement Altern Med.2017, 17(1):384
  • bioRxiv - Molecular Biology2023, 535548.
  • SRM Institute of Sci&Tech2022, 34(1): 32-37
  • J Nat Med.2022, 76(1):59-67.
  • Phytomedicine2022, 104:154318
  • Pak J Pharm Sci.2023, 36(1):51-57.
  • Molecules.2020, 25(11):2599.
  • Evid Based Complement Alternat Med.2020, 2020:9416962.
  • Mol Med Rep.2022, 25(1):8.
  • Vietnam Journal of Science2022,64(2):69-75.
  • Biomol Ther (Seoul).2019, 10.4062
  • Molecules.2019, 24(6):E1155
  • Pharmacognosy Magazine2017, 13(52):868-874
  • RSC Adv.2023, 13(9):6317-6326.
  • South African J of Botany2020, 135:50-57
  • In Vitro Cellular & Developmental Biology - Plant2022, 58:972-988.
  • Asian Pac J Tropical Bio.2020, 10(6):239-247
  • ...
  • 生物活性
    Description: Alizarin 2-methyl ether enhances adipocyte differentiation by up to 131%, it could be beneficial in the treatment of diabetes.
    In vitro:
    Nat Prod Res. 2012;26(18):1750-4.
    Anthraquinones from Morinda officinalis roots enhance adipocyte differentiation in 3T3-L1 cells.[Pubmed: 22008000]
    To search for anti-diabetic and insulin-sensitising natural products, the effect on adipocyte differentiation was investigated by assessing fat accumulation in 3T3-L1 preadipocytes using Oil Red O staining.
    METHODS AND RESULTS:
    Fractionation and separation of n-hexane and CHCl₃ fractions of Morinda officinalis (Rubiaceae) using several chromatographic methods led to the isolation of three anthraquinones, 1,2-dimethoxyanthraquinone (1), Alizarin 2-methyl ether (2) and rubiadin-1-methyl ether (3). Among them, Alizarin 2-methyl ether (2) showed the strongest enhancing activity, followed by rubiadin-1-methyl ether (3) and 1,2-dimethoxyanthraquinone (1). At a concentration of 100 µM, Alizarin 2-methyl ether (2) enhanced adipocyte differentiation by up to 131% (compared to insulin-treated cells).
    CONCLUSIONS:
    Thus, these compounds could be beneficial in the treatment of diabetes.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.9339 mL 19.6696 mL 39.3391 mL 78.6782 mL 98.3478 mL
    5 mM 0.7868 mL 3.9339 mL 7.8678 mL 15.7356 mL 19.6696 mL
    10 mM 0.3934 mL 1.967 mL 3.9339 mL 7.8678 mL 9.8348 mL
    50 mM 0.0787 mL 0.3934 mL 0.7868 mL 1.5736 mL 1.967 mL
    100 mM 0.0393 mL 0.1967 mL 0.3934 mL 0.7868 mL 0.9835 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    1,2-二羟基蒽醌,茜素; Alizarin CFN92568 72-48-0 C14H8O4 = 240.2 20mg QQ客服:2056216494
    茜素-1-甲醚; 2-Hydroxy-1-methoxyanthraquinone CFN92111 6170-06-5 C15H10O4 = 254.2 10mg QQ客服:215959384
    1-羟基-2-甲氧基蒽醌; Alizarin 2-methyl ether CFN92569 6003-11-8 C15H10O4 = 254.2 5mg QQ客服:1413575084
    异茜草素; Xanthopurpurin CFN96430 518-83-2 C14H8O4 = 240.21 5mg QQ客服:2159513211
    9,10-Anthracenedione; 9,10-Anthracenedione CFN92557 19852-76-7 C16H12O5 = 284.3 5mg QQ客服:1457312923
    吡啉; Purpurin CFN92566 81-54-9 C14H8O5 = 256.2 20mg QQ客服:2056216494
    1,8-二羟基蒽醌; Dantron CFN99271 117-10-2 C14H8O4 = 240.2 20mg QQ客服:1457312923

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