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  • 萝巴新; 阿吗碱

    Ajmalicine

    萝巴新; 阿吗碱
    产品编号 CFN98761
    CAS编号 483-04-5
    分子式 = 分子量 C21H24N2O3 = 352.4
    产品纯度 >=98%
    物理属性 Cryst.
    化合物类型 Alkaloids
    植物来源 The herbs of Catharanthus roseus
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    萝巴新; 阿吗碱 CFN98761 483-04-5 1mg QQ客服:2159513211
    萝巴新; 阿吗碱 CFN98761 483-04-5 5mg QQ客服:2159513211
    萝巴新; 阿吗碱 CFN98761 483-04-5 10mg QQ客服:2159513211
    萝巴新; 阿吗碱 CFN98761 483-04-5 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Seoul National University (Korea)
  • University of Helsinki (Finland)
  • The Institute of Cancer Research (United Kingdom)
  • Georgia Institute of Technology (USA)
  • Nanjing University of Chinese Medicine (China)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • Mahatma Gandhi University (India)
  • Universidade Católica Portuguesa (Portugal)
  • Seoul National University of Science and Technology (Korea)
  • University of Toulouse (France)
  • Wageningen University (Netherlands)
  • University of Vigo (Spain)
  • Monash University Sunway Campus (Malaysia)
  • Universidad de Antioquia (Colombia)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Scientific World Journal.2014, 2014:654193
  • Faculty of Chem. & Nat. Resource Eng.2014, 62
  • Pharmacogn Mag.2015, 11:S585-91
  • Phytochemistry Letters2015, 243-247
  • University of Limpopo2016, 1-237
  • Korean J. of Food Sci. and Tech2016, 172-177
  • Acta Chromatographica2016, 29(3)
  • Braz J Med Biol Res. 2016, 49(7)
  • J Separation Science & Technology2016, 51:1579-1588
  • Current Pharmaceutical Analysis2017, 13(5)
  • J Ethnopharmacol.2017, 206:327-336
  • J Sci Food Agric.2017, 97(5):1656-1662
  • Sci Rep. 2018, 10590
  • BMC Pharmacol Toxicol.2018, 19(1):5
  • Molecules.2018, 23(2)
  • Nat Prod Sci.2018, 24(3):206
  • International Food Research Journal2018, 25(6):2560-2571
  • Phytomedicine.2018, 47:48-57
  • Front Pharmacol.2019, 10:1226
  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1113:1-13
  • Int J Biol Macromol.2019, 126:653-661
  • Korean Journal of Pharmacognosy2019, 50(4):285-290
  • Saudi Pharm J2020, 10.1016
  • ...
  • 生物活性
    Description: Ajmalicine, also known as δ-yohimbine or raubasine, is an antihypertensive drug used in the treatment of high blood pressure.
    Targets: P450 (e.g. CYP17)
    In vitro:
    Appl Microbiol Biotechnol. 2015 May 16.
    Effects of β-cyclodextrin and methyl jasmonate on the production of vindoline, catharanthine, and ajmalicine in Catharanthus roseus cambial meristematic cell cultures.[Pubmed: 25981997]

    METHODS AND RESULTS:
    Long-term stable cell growth and production of vindoline, catharanthine, and Ajmalicine of cambial meristematic cells (CMCs) from Catharanthus roseus were observed after 2 years of culture. C. roseus CMCs were treated with β-cyclodextrin (β-CD) and methyl jasmonate (MeJA) individually or in combination and were cultured both in conventional Erlenmeyer flasks (100, 250, and 500 mL) and in a 5-L stirred hybrid airlift bioreactor. CMCs of C. roseus cultured in the bioreactor showed higher yields of vindoline, catharanthine, and Ajmalicine than those cultured in flasks.
    CONCLUSIONS:
    CMCs of C. roseus cultured in the bioreactor and treated with 10 mM β-CD and 150 μM MeJA gave the highest yields of vindoline (7.45 mg/L), catharanthine (1.76 mg/L), and Ajmalicine (58.98 mg/L), concentrations that were 799, 654, and 426 % higher, respectively, than yields of CMCs cultured in 100-mL flasks without elicitors.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.8377 mL 14.1884 mL 28.3768 mL 56.7537 mL 70.9421 mL
    5 mM 0.5675 mL 2.8377 mL 5.6754 mL 11.3507 mL 14.1884 mL
    10 mM 0.2838 mL 1.4188 mL 2.8377 mL 5.6754 mL 7.0942 mL
    50 mM 0.0568 mL 0.2838 mL 0.5675 mL 1.1351 mL 1.4188 mL
    100 mM 0.0284 mL 0.1419 mL 0.2838 mL 0.5675 mL 0.7094 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Rauvotetraphylline E; Rauvotetraphylline E CFN96746 1422506-53-3 C20H19N2O3 = 335.4 5mg QQ客服:1148253675
    鸭脚木碱; Alstonine CFN97709 642-18-2 C21H21N2O3 = 349.4 5mg QQ客服:1413575084
    阿枯米精; Akuammigine CFN97710 642-17-1 C21H24N2O3 = 352.43 5mg QQ客服:3257982914
    Serpentinic acid; Serpentinic acid CFN97721 605-14-1 C20H19N2O3 = 335.38 5mg QQ客服:2932563308
    19-表阿马碱; Mayumbine CFN98283 25532-45-0 C21H24N2O3 = 352.4 5mg QQ客服:2932563308
    蛇根亭碱; Serpentinine CFN98499 36519-42-3 C42H44N4O5 = 684.8 5mg QQ客服:1413575084
    (4R)-阿马碱N-氧化物; 4,R-ajmalicine N-oxide CFN98652 41590-29-8 C21H24N2O4 = 368.4 5mg QQ客服:1148253675
    阿立新碱; Aricine CFN98760 482-91-7 C22H26N2O4 = 382.5 5mg QQ客服:2932563308
    萝巴新; 阿吗碱; Ajmalicine CFN98761 483-04-5 C21H24N2O3 = 352.4 5mg QQ客服:215959384
    蛇纹石素; Serpentine CFN99867 18786-24-8 C21H21N2O3 = 349.4 5mg QQ客服:2159513211

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