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  • 2',3,5,6',7-四羟基二氢黄烷酮

    2',3,5,6',7-Pentahydroxyflavanone

    2',3,5,6',7-四羟基二氢黄烷酮
    产品编号 CFN97277
    CAS编号 80366-15-0
    分子式 = 分子量 C15H12O7 = 304.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The roots of Scutellaria baicalensis Georgi
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    2',3,5,6',7-四羟基二氢黄烷酮 CFN97277 80366-15-0 1mg QQ客服:215959384
    2',3,5,6',7-四羟基二氢黄烷酮 CFN97277 80366-15-0 5mg QQ客服:215959384
    2',3,5,6',7-四羟基二氢黄烷酮 CFN97277 80366-15-0 10mg QQ客服:215959384
    2',3,5,6',7-四羟基二氢黄烷酮 CFN97277 80366-15-0 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of the Basque Country (Spain)
  • University of Toulouse (France)
  • Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)
  • The Ohio State University (USA)
  • University of Auckland (New Zealand)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • BMC Complement Altern Med.2017, 17(1):393
  • Nat Commun.2021, 12(1):681.
  • J Drug Target.2016, 24:1-28
  • Food Structure2023, 36:100324.
  • Preprints2022, 2022030063.
  • Nutrients.2017, 10(1)
  • Int J Mol Sci.2018, 19(2)
  • PLoS One.2021, 16(9):e0257243.
  • Antioxidants (Basel).2021, 10(3):379.
  • Aquaculture2019, 510:392-399
  • International J of Green Pharmacy2019, 13(3)
  • J of Health Science and Alternative Medicine2019, 1(1)
  • Plants (Basel).2021, 10(5):951.
  • Phytomedicine Plus2022, 2(1):100207.
  • Oncol Rep.2019, 41(4):2453-2463
  • Molecules.2021, 26(2):313.
  • Environ Toxicol.2023, 23929.
  • J Pharmaceutical and Biomedical Analysis2022, 114631.
  • Molecules.2022, 27(7):2360.
  • J Ethnopharmacol.2023, 317:116789.
  • J Pharm Biomed Anal.2021, 196:113931.
  • BMC Complement Altern Med.2014, 14:242
  • Life (Basel).2022, 12(10):1630.
  • ...
  • 生物活性
    Description: (2R,3R)-2',3,5,6'7-pentahydroxyflavanone(2',3,5,6',7-Pentahydroxyflavanone) can inhibit the histamine release from rat mast cells induced by compound 48/80. It inhibits the lipid peroxide formation by Feand ascorbic acid, it also inhibits the lipid peroxide formation induced by adenosine diphosphate and reduces nicotinamide adenine dinucleotide phosphate in rat liver homogenate.
    Targets: NO
    In vitro:
    Chem. Pharm. Bull., 1984, 32(12):5051-4.
    Scutellariae radix. X. Inhibitory effects of various flavonoids on histamine release from rat peritoneal mast cells in vitro.[Reference: WebLink]
    The effects of various flavonoids isolated from the roots of Scutellaria baicalensis on the histamine release from mast cells were investigated.
    METHODS AND RESULTS:
    Many of the flavonoids (wogonin, wogonin-7-O-D-glucuronide, baicalein, skullcapflavanone II, (2S)-2',5,6',7-tetrahydroxyflavanone, (2R,3R)-2',3,5,6',7-Pentahydroxyflavanone and 2',5,5',7-tetrahydroxy-6'-8-dimethoxyflavone) inhibited the histamine release from rat mast cells induced by compound 48/80.
    Chem Pharm Bull (Tokyo). 1982 May;30(5):1792-5.
    Studies on Scutellariae radix. VI. Effects of flavanone compounds on lipid peroxidation in rat liver.[Reference: WebLink]
    Compounds (I and II) which inhibited lipid peroxides formation (in in vitro experiments) were isolated together with various flavonoids from the roots of Scutellaria baicalensis GEORGI.
    METHODS AND RESULTS:
    From the analytical and physical data, compounds I and II were identified as (2S)-2', 5, 6', 7-tetrahydroxyflavanone and (2R, 3R)-2',3,5,6',7-Pentahydroxyflavanone, respectively. Compound II inhibited the lipid peroxide formation by Feand ascorbic acid. Compounds I and II inhibited the lipid peroxide formation induced by adenosine diphosphate and reduced nicotinamide adenine dinucleotide phosphate in rat liver homogenate.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.2862 mL 16.4312 mL 32.8623 mL 65.7246 mL 82.1558 mL
    5 mM 0.6572 mL 3.2862 mL 6.5725 mL 13.1449 mL 16.4312 mL
    10 mM 0.3286 mL 1.6431 mL 3.2862 mL 6.5725 mL 8.2156 mL
    50 mM 0.0657 mL 0.3286 mL 0.6572 mL 1.3145 mL 1.6431 mL
    100 mM 0.0329 mL 0.1643 mL 0.3286 mL 0.6572 mL 0.8216 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    雪松素; Cedrin CFN97872 75513-81-4 C16H14O8 = 334.3 5mg QQ客服:2159513211
    (-)-二氢槲皮素; (-)-Dihydroquercetin CFN92413 111003-33-9 C15H12O7 = 304.3 5mg QQ客服:1457312923
    花旗松素; Taxifolin CFN98734 480-18-2 C15H12O7 = 304.3 20mg QQ客服:1413575084
    李属素; Padmatin CFN97280 80453-44-7 C16H14O7 = 318.3 5mg QQ客服:1413575084
    雪松素 ; Deodarin CFN96563 33788-39-5 C16H14O7 = 318.29 5mg QQ客服:3257982914
    2',3,5,6',7-四羟基二氢黄烷酮; 2',3,5,6',7-Pentahydroxyflavanone CFN97277 80366-15-0 C15H12O7 = 304.3 5mg QQ客服:2159513211
    二氢桑色素; Dihydromorin CFN99854 18422-83-8 C15H12O7 = 304.3 5mg QQ客服:2056216494
    二氢柽柳黄素; Dihydrotamarixetin CFN97194 70411-27-7 C16H14O7 = 318.3 5mg QQ客服:1413575084
    艾纳香素B; Blumeatin B CFN97274 79995-67-8 C17H16O7 = 332.3 5mg QQ客服:215959384
    刺槐亭; Dihydrorobinetin CFN98671 4382-33-6 C15H12O7 = 304.3 5mg QQ客服:2159513211

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