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  • 1,5,6-三羟基-3-甲氧基呫吨酮

    1,5,6-Trihydroxy-3-methoxyxanthone

    1,5,6-三羟基-3-甲氧基呫吨酮
    产品编号 CFN89549
    CAS编号 50868-52-5
    分子式 = 分子量 C14H10O6 = 274.22
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Xanthones
    植物来源 The herbs of Mangifera indica
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    1,5,6-三羟基-3-甲氧基呫吨酮 CFN89549 50868-52-5 1mg QQ客服:1457312923
    1,5,6-三羟基-3-甲氧基呫吨酮 CFN89549 50868-52-5 5mg QQ客服:1457312923
    1,5,6-三羟基-3-甲氧基呫吨酮 CFN89549 50868-52-5 10mg QQ客服:1457312923
    1,5,6-三羟基-3-甲氧基呫吨酮 CFN89549 50868-52-5 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • BMC Complement Altern Med.2018, 18(1):221
  • LWT - Food Science and Technology2022, 164:113627
  • Vet World.2023, 16(3):618-630.
  • Tumour Biol.2015, 36(12):9385-93
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  • Sci Rep.2018, 8(1)
  • J Nat Prod.2023, 86(2):264-275.
  • Oncotarget.2017, 8(53):90925-90947
  • Front Immunol.2017, 8:1542
  • Sci Rep.2019, 9(1):18080
  • PLoS One.2022, 17(4):e0267007.
  • Molecules.2021, 26(4):816.
  • Molecules.2022, 27(21):7643.
  • Food Chem Toxicol.2023, 176:113785.
  • Int J Cosmet Sci.2022, doi:10.1111/ics.12827.
  • J Nat Med.2018, 72(3):734-744
  • Processes 2021, 9(5),894.
  • ...
  • 生物活性
    Description: 1,5,6-Trihydroxy-3-methoxyxanthone exhibits scavenging activity at 10 uM, it can reduce the viability of HL-60 cells significantly with IC50 values of 28.9 uM.
    Targets: ROS
    In vitro:
    Food Science & Biotechnology, 2013, 22(4):945-949.
    Isolation of xanthones from adventitious roots of St. John’s Wort (Hypericum perforatum L.) and their antioxidant and cytotoxic activities.[Reference: WebLink]

    METHODS AND RESULTS:
    In this phytochemical study, 5 xanthones, 1,3,5,6-tetrahydroxyxanthone [1], 1,5,6-Trihydroxy-3-methoxyxanthone [2], ferrxanthone [3], brasilixanthone B [4], and neolancerin [5] were isolated from adventitious roots of St. John’s wort (Hypericum perforatum L.). Compound 1–5 were evaluated for antioxidant activities using the intracellular reactive oxygen species (ROS) radical scavenging 2′,7′-dichlorfluorescein-diacetate (DCFDA) assay and for cytotoxic activity against the HL-60 human promyelocytic leukemia cells.
    CONCLUSIONS:
    Among them, compound 1–4 exhibited scavenging activity with inhibition values of 27.4–33.2% at 10 μM; compound 1, 2, and 4 reduced the viability of HL-60 cells significantly, with IC50 values of 31.5, 28.9, and 27.7 μM, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.6467 mL 18.2335 mL 36.4671 mL 72.9341 mL 91.1677 mL
    5 mM 0.7293 mL 3.6467 mL 7.2934 mL 14.5868 mL 18.2335 mL
    10 mM 0.3647 mL 1.8234 mL 3.6467 mL 7.2934 mL 9.1168 mL
    50 mM 0.0729 mL 0.3647 mL 0.7293 mL 1.4587 mL 1.8234 mL
    100 mM 0.0365 mL 0.1823 mL 0.3647 mL 0.7293 mL 0.9117 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    1,3,5,6-四羟基氧杂蒽酮; 1,3,5,6-Tetrahydroxyxanthone CFN92539 5084-31-1 C13H8O6 = 260.2 5mg QQ客服:1413575084
    1,3,6-三羟基-5-甲氧基氧杂蒽酮; 1,3,6-Trihydroxy-5-methoxyxanthone CFN92540 41357-84-0 C14H10O6 = 274.2 5mg QQ客服:1457312923
    3,8-二羟基-2,4,6-三甲氧基氧杂蒽酮; 3,8-Dihydroxy-2,4,6-trimethoxyxanthone CFN92556 65008-17-5 C16H14O7 = 318.3 5mg QQ客服:215959384
    1,6,7-三羟基氧杂蒽酮; 1,6,7-Trihydroxyxanthone CFN98284 25577-04-2 C13H8O5 = 244.2 5mg QQ客服:2056216494
    1,3,6,7-四羟基氧杂蒽酮; Norathyriol CFN98468 3542-72-1 C13H8O6 = 260.2 5mg QQ客服:1413575084
    Montixanthone; Montixanthone CFN91903 876305-36-1 C14H10O6 = 274.23 5mg QQ客服:3257982914
    3,6-二羟基-1,7-二甲氧基呫吨酮; 3,6-Dihydroxy-1,7-dimethoxyxanthone CFN89303 262292-34-2 C15H12O6 = 288.25 5mg QQ客服:2056216494
    Onjixanthone II; Onjixanthone II CFN89276 136083-93-7 C15H12O7 = 304.25 5mg QQ客服:1413575084
    6-羟基-1,2,3,7-四甲氧基咕吨酮; 6-Hydroxy-1,2,3,7-tetramethoxyxanthone CFN89282 64756-87-2 C17H16O7 = 332.30 5mg QQ客服:3257982914
    1,2,3,6,7-Pentamethoxyxanthone; 1,2,3,6,7-Pentamethoxyxanthone CFN89241 64756-86-1 C18H18O7 = 346.33 5mg QQ客服:2056216494

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